Cognitive dysfunction: a growing link between diabetes and Alzheimer's disease

K Jash, P Gondaliya, P Kirave… - Drug development …, 2020 - Wiley Online Library
Diabetes mellitus (DM) is a gradually rising metabolic disease which is currently affecting
millions of people worldwide. Diabetes is associated with various complications like …

[HTML][HTML] Gradual disturbances of the amplitude of low-frequency fluctuations (ALFF) and fractional ALFF in Alzheimer spectrum

L Yang, Y Yan, Y Wang, X Hu, J Lu, P Chan… - Frontiers in …, 2018 - frontiersin.org
Background: Alzheimer's disease (AD) is a common neurodegenerative disease in which
the brain undergoes alterations for decades before symptoms become obvious. Subjective …

Multicenter and multichannel pooling GCN for early AD diagnosis based on dual-modality fused brain network

X Song, F Zhou, AF Frangi, J Cao… - … on Medical Imaging, 2022 - ieeexplore.ieee.org
For significant memory concern (SMC) and mild cognitive impairment (MCI), their
classification performance is limited by confounding features, diverse imaging protocols, and …

In vivo synaptic density loss correlates with impaired functional and related structural connectivity in Alzheimer's disease

J Zhang, J Wang, X Xu, Z You… - Journal of Cerebral …, 2023 - journals.sagepub.com
Synapse loss has been considered as a major pathological change in Alzheimer's disease
(AD). It remains unclear about whether and how synapse loss relates to functional and …

Grey matter loss at different stages of cognitive decline: a role for the thalamus in developing Alzheimer's disease

LA van de Mortel, RM Thomas… - Journal of …, 2021 - content.iospress.com
Background: Alzheimer's disease (AD) is characterized by cognitive impairment and large
loss of grey matter volume and is the most prevalent form of dementia worldwide. Mild …

Modulation of functional activity and connectivity by acupuncture in patients with Alzheimer disease as measured by resting-state fMRI

W Zheng, Z Su, X Liu, H Zhang, Y Han, H Song, J Lu… - PloS one, 2018 - journals.plos.org
Acupuncture has been used in the therapy of Alzheimer disease (AD); however, its neural
mechanisms are still unclear. The aim of this study is to examine the effect of acupuncture on …

Disrupted patterns of rich-club and diverse-club organizations in subjective cognitive decline and amnestic mild cognitive impairment

C Xue, H Sun, G Hu, W Qi, Y Yue, J Rao… - Frontiers in …, 2020 - frontiersin.org
Background Subjective cognitive decline (SCD) and amnestic mild cognitive impairment
(aMCI) were considered to be a continuum of Alzheimer's disease (AD) spectrum. The …

Compensation and brain aging: A review and analysis of evidence.

LB Zahodne, PA Reuter-Lorenz - 2019 - psycnet.apa.org
Compensation has long been recognized as a cornerstone of successful late-life
development, figuring prominently in behavioral research and theory on cognitive aging …

[HTML][HTML] Autonomic function predicts cognitive decline in mild cognitive impairment: Evidence from power spectral analysis of heart rate variability in a longitudinal …

P Nicolini, T Lucchi, C Abbate, S Inglese… - Frontiers in Aging …, 2022 - frontiersin.org
Background: Despite the emerging clinical relevance of heart rate variability (HRV) as a
potential biomarker of cognitive decline and as a candidate target for intervention, there is a …

Repeated anodal high-definition transcranial direct current stimulation over the left dorsolateral prefrontal cortex in mild cognitive impairment patients increased …

F He, Y Li, C Li, L Fan, T Liu, J Wang - PLoS One, 2021 - journals.plos.org
Transcranial direct current stimulation (tDCS) can improve cognitive function. However, it is
not clear how high-definition tDCS (HD-tDCS) regulates the cognitive function and its neural …