The role of exosomes and exosomal microRNA in cardiovascular disease

D Zheng, M Huo, B Li, W Wang, H Piao… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are small vesicles (30–150 nm in diameter) enclosed by a lipid membrane
bilayer, secreted by most cells in the body. They carry various molecules, including proteins …

p38 MAPK pathway in the heart: new insights in health and disease

R Romero-Becerra, AM Santamans… - International Journal of …, 2020 - mdpi.com
The p38 mitogen-activated kinase (MAPK) family controls cell adaptation to stress stimuli.
p38 function has been studied in depth in relation to cardiac development and function. The …

[HTML][HTML] Mechanisms of ferroptosis regulating oxidative stress and energy metabolism in myocardial ischemia-reperfusion injury and a novel perspective of natural …

T Zhang, W Deng, Y Deng, Y Liu, S Xiao, Y Luo… - Biomedicine & …, 2023 - Elsevier
Acute myocardial infarction remains the leading cause of death in humans. Timely
restoration of blood perfusion to ischemic myocardium remains the most effective strategy in …

Cardiovascular toxicity and mechanism of bisphenol A and emerging risk of bisphenol S

YF Zhang, C Shan, Y Wang, LL Qian, DD Jia… - Science of the total …, 2020 - Elsevier
Epidemiological and animal studies indicate that increased exposure to bisphenol A (BPA)
induces various human cardiovascular diseases (CVDs), including myocardial infarction …

Baicalin relieves hypoxia-aroused H9c2 cell apoptosis by activating Nrf2/HO-1-mediated HIF1α/BNIP3 pathway

H Yu, B Chen, Q Ren - Artificial cells, nanomedicine, and …, 2019 - Taylor & Francis
Background Myocardial ischemia is the main reason for ischemic heart disease. Baicalin is
a plant-derived flavonoid with cardio-protective activity. Herein, we tested the influences of …

A comprehensive review on schisandrin B and its biological properties

MI Nasser, S Zhu, C Chen, M Zhao… - … Medicine and Cellular …, 2020 - Wiley Online Library
Nature is a vast source of bioactive molecules and has provided an active and efficient
reservoir for drug discovery. Among natural compounds, one of the most promising is …

Dynamic status of SII and SIRI alters the risk of cardiovascular diseases: evidence from kailuan cohort study

J Li, D He, J Yu, S Chen, Q Wu, Z Cheng… - Journal of …, 2023 - Taylor & Francis
Background Two novel systemic inflammation indices, SII and SIRI, are associated with
increased risk of cardiovascular diseases (CVD). However, SII and SIRI are prone to change …

Resistin: Potential biomarker and therapeutic target in atherosclerosis

L Zhou, JY Li, PP He, XH Yu, CK Tang - Clinica chimica acta, 2021 - Elsevier
Resistin, a cysteine-rich secretory protein, has a pleiotropic role in humans. Resistin usually
presents as trimer or hexamer in plasma, and targets specific receptors Toll Like Receptor 4 …

Injectable smart stimuli-responsive hydrogels: pioneering advancements in biomedical applications

J Liu, C Du, W Huang, Y Lei - Biomaterials Science, 2024 - pubs.rsc.org
Hydrogels have established their significance as prominent biomaterials within the realm of
biomedical research. However, injectable hydrogels have garnered greater attention …

C-Phycocyanin prevents acute myocardial infarction-induced oxidative stress, inflammation and cardiac damage

V Blas-Valdivia, DN Moran-Dorantes… - Pharmaceutical …, 2022 - Taylor & Francis
Context C-Phycocyanin is a protein with anti-scavenger, antioxidant and anti-inflammatory
actions against agents that cause cellular damage. The cardioprotective action of C …