In bone, skin, and connective tissues, type I collagen is not only the most abundant collagen,
but it is also essential for tissue integrity. Type I collagen is an interstitial matrix molecule that …

ABSTRACT The Apolipoprotein E ε4 (APOE ε4) haplotype is the strongest genetic risk factor
for late-onset Alzheimer's disease (AD). The Translocase of Outer Mitochondrial Membrane …

Understanding the genomic architecture and molecular mechanisms of cognitive functioning
in healthy individuals is critical for developing tailored interventions to enhance cognitive …

Background Disease modifying treatments for dementia are only just surfacing, and their
development is still significantly hindered by the lack of validated tools for identification of …

Unlocking the potential of metal nanoparticles (NPs) in biomedical applications represents a
leading endeavor in contemporary research. Among these, gold NPs (AuNPs) and silver …

Alzheimer's disease (AD) is one of the most serious neurodegenerative diseases in the
world and has a strong genetic predisposition. At present, there is still no effective method …

Beta-Propeller Protein-Associated Neurodegeneration (BPAN) is one of the commonest
forms of Neurodegeneration with Brain Iron Accumulation, caused by mutations in the gene …

Using well-phenotyped population-based studies offers unique opportunities to improve our
understanding of the extracellular matrix (ECM). In population-based studies, it is possible to …