Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

Nanotechnology refers to the fabrication, characterization, and application of substances in
nanometer scale dimensions for various ends. The influence of nanotechnology on the …

Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …

There have been many attempts to provide sufficient nutrients, especially oxygen, to
engineered large tissues to overcome the effects of hypoxia or poor vascularization …

Abstract 3D bioprinting holds remarkable promise for rapid fabrication of 3D tissue
engineering constructs. Given its scalability, reproducibility, and precise multi-dimensional …

Diabetic wounds are among the major healthcare challenges, consuming billions of dollars
of resources and resulting in high numbers of morbidity and mortality every year. Lack of …

Abstract Engineering three-dimensional (3D) tissues in clinically relevant sizes have
demonstrated to be an effective solution to bridge the gap between organ demand and the …

Tissue engineering (TE) has provided promising strategies for regenerating tissue defects,
but few TE approaches have been translated for clinical applications. One major barrier in …

To date, hydrogels have opened new prospects for potential applications for drug delivery.
The thermo-sensitive hydrogels have the great potential to provide more effective and …

In this study, we present the photosynthetic oxygen (O 2) supply to mammalian cells within a
volumetric extracellular matrix-like construct, whereby a three-dimensional (3D)-bioprinted …