Synthesis, molecular docking, analgesic, anti-inflammatory, and ulcerogenic evaluation of thiophene-pyrazole candidates as COX, 5-LOX, and TNF-α inhibitors

MJN Khadri, R Ramu, NA Simha, SA Khanum - Inflammopharmacology, 2024 - Springer
The thiophene bearing pyrazole derivatives (7a-j) were synthesized and examined for their
in vitro cyclooxygenase, 5-lipoxygenase, and tumour inducing factor-α inhibitory activities …

[HTML][HTML] Antioxidant mediated protective effect of Bridelia tomentosa leaf extract against carbofuran induced oxidative hepatic toxicity

M Mondal, MS Hossen, MA Rahman, S Saha… - Toxicology Reports, 2021 - Elsevier
Bridelia tomentosa (B. tomentosa) is a traditional medicinal plant for treating diverse
ailments. Hence, we designed our study to scrutinize the protective effect of the methanol …

Exploring Caralluma europaea (Guss.) NE Br. as a potential source of bioactive molecules: In vitro antioxidant and antidiabetic properties, and phenolic profile of …

LA Dra, MJ Rodrigues, N da Rosa Neng… - Industrial Crops and …, 2019 - Elsevier
Abstract Caralluma europaea (Guss.) NE Br is a succulent medicinal species used in the
Moroccan traditional medicine for its anticancer and antidiabetic properties. In this work, this …

Toxicity of two drugs towards the marine filter feeder Mytilus spp, using biochemical and shell integrity parameters

D Daniel, JC Campos, PC Costa, B Nunes - Environmental Pollution, 2022 - Elsevier
The increasing presence of anthropogenic contaminants in the environment may constitute
a challenge to non-target biota, considering that most contaminants can exert deleterious …

Recent investigation on heterocycles with one nitrogen [piperidine, pyridine and quinoline], two nitrogen [1, 3, 4-thiadiazole and pyrazole] and three nitrogen [1, 2, 4 …

Zabiulla, FH Al-Ostoot, M Al-Ghorbani… - Journal of the Iranian …, 2022 - Springer
Heterocycles form by far the largest of classical divisions of organic chemistry and are of
immense importance biologically and industrially, and about one half of over six million …