The risk for major depression is both genetically and environmentally determined. It has
been proposed that epigenetic mechanisms could mediate the lasting increases in …

Albinism is a pigment disorder affecting eye, skin and/or hair. Patients usually have
decreased melanin in affected tissues and suffer from severe visual abnormalities, including …

Fatty acids have long been considered essential to brain development; however, the
involvement of their synthesis in nervous system formation is unclear. We generate mice …

Abstract The N6-methyladenosine (m6A) modification plays important regulatory roles in
gene expression, cancer occurrence and metastasis. Herein, we aimed to explore the …

Background: Osimertinib-based therapy effectively improves the prognosis of lung
adenocarcinoma (LUAD) patients with epidermal growth factor receptor mutations. However …

We present the first large-scale methylome-wide association studies (MWAS) for major
depressive disorder (MDD) to identify sites of potential importance for MDD etiology. Using a …

Abstract miR-124 is a miRNA predominantly expressed in the nervous system and accounts
for more than a quarter of the total miRNAs in the brain. It regulates neurogenesis, neuronal …

Post-surgical adhesions are internal scar tissue and a major health and economic burden.
Adhesions affect and involve the peritoneal lining of the abdominal cavity, which consists of …

Neuronal growth cones are essential for nerve growth and regeneration, as well as for the
formation and rearrangement of the neural network. To elucidate phosphorylation …

Intracellular trafficking is essential for cell structure and function. In order to perform key
tasks such as phagocytosis, secretion or migration, cells must coordinate their intracellular …