Opportunities and challenges in translational science
CP Austin - Clinical and Translational Science, 2021 - Wiley Online Library
The mission of translational science is to bring predictivity and efficiency to the development
and dissemination of interventions that improve human health. Ten years ago this year, the …
and dissemination of interventions that improve human health. Ten years ago this year, the …
[HTML][HTML] A machine learning and explainable artificial intelligence triage-prediction system for COVID-19
COVID-19 is a respiratory disease caused by the SARS-CoV-2 contagion, severely
disrupted the healthcare infrastructure. Various countries have developed COVID-19 …
disrupted the healthcare infrastructure. Various countries have developed COVID-19 …
Association between immune dysfunction and COVID-19 breakthrough infection after SARS-CoV-2 vaccination in the US
Importance Persons with immune dysfunction have a higher risk for severe COVID-19
outcomes. However, these patients were largely excluded from SARS-CoV-2 vaccine …
outcomes. However, these patients were largely excluded from SARS-CoV-2 vaccine …
[HTML][HTML] Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19
Longitudinal analyses of the innate immune system, including the earliest time points, are
essential to understand the immunopathogenesis and clinical course of coronavirus disease …
essential to understand the immunopathogenesis and clinical course of coronavirus disease …
Outcomes of COVID-19 in patients with cancer: report from the National COVID Cohort Collaborative (N3C)
PURPOSE Variation in risk of adverse clinical outcomes in patients with cancer and COVID-
19 has been reported from relatively small cohorts. The NCATS'National COVID Cohort …
19 has been reported from relatively small cohorts. The NCATS'National COVID Cohort …
Outcomes of SARS-CoV-2 infection in patients with chronic liver disease and cirrhosis: a national COVID cohort collaborative study
Background & Aims In patients with chronic liver disease (CLD) with or without cirrhosis,
existing studies on the outcomes with severe acute respiratory syndrome coronavirus 2 …
existing studies on the outcomes with severe acute respiratory syndrome coronavirus 2 …
Long-term use of immunosuppressive medicines and in-hospital COVID-19 outcomes: a retrospective cohort study using data from the National COVID Cohort …
KM Andersen, BA Bates, ES Rashidi… - The Lancet …, 2022 - thelancet.com
Background Many individuals take long-term immunosuppressive medications. We
evaluated whether these individuals have worse outcomes when hospitalised with COVID …
evaluated whether these individuals have worse outcomes when hospitalised with COVID …
Association between glucagon-like peptide 1 receptor agonist and sodium–glucose cotransporter 2 inhibitor use and COVID-19 outcomes
OBJECTIVE To determine the respective associations of premorbid glucagon-like peptide-1
receptor agonist (GLP1-RA) and sodium–glucose cotransporter 2 inhibitor (SGLT2i) use …
receptor agonist (GLP1-RA) and sodium–glucose cotransporter 2 inhibitor (SGLT2i) use …
A serum proteome signature to predict mortality in severe COVID-19 patients
Here, we recorded serum proteome profiles of 33 severe COVID-19 patients admitted to
respiratory and intensive care units because of respiratory failure. We received, for most …
respiratory and intensive care units because of respiratory failure. We received, for most …
Rituximab is associated with worse COVID-19 outcomes in patients with rheumatoid arthritis: a retrospective, nationally sampled cohort study from the US National …
Objective To assess whether rituximab (RTX) is associated with worse COVID-19 outcomes
among patients with rheumatoid arthritis (RA). Methods We used the National COVID Cohort …
among patients with rheumatoid arthritis (RA). Methods We used the National COVID Cohort …