Aloe‐emodin: a review of its pharmacology, toxicity, and pharmacokinetics

X Dong, Y Zeng, Y Liu, L You, X Yin… - Phytotherapy …, 2020 - Wiley Online Library
Aloe‐emodin is a naturally anthraquinone derivative and an active ingredient of Chinese
herbs, such as Cassia occidentalis, Rheum palmatum L., Aloe vera, and Polygonum …

Estrogenic endocrine disruptors: Molecular mechanisms of action

R Kiyama, Y Wada-Kiyama - Environment International, 2015 - Elsevier
A comprehensive summary of more than 450 estrogenic chemicals including estrogenic
endocrine disruptors is provided here to understand the complex and profound impact of …

Botany, phytochemistry, pharmacology, and potential application of Polygonum cuspidatum Sieb. et Zucc.: a review

W Peng, R Qin, X Li, H Zhou - Journal of ethnopharmacology, 2013 - Elsevier
Abstract Ethnopharmacological relevance Polygonum cuspidatum Sieb. et Zucc.(Polygonum
cuspidatum), also known as Reynoutria japonica Houtt and Huzhang in China, is a …

Phytoestrogens: a review of the present state of research

AL Ososki, EJ Kennelly - Phytotherapy Research: An …, 2003 - Wiley Online Library
Phytoestrogens are a diverse group of plant-derived compounds that structurally or
functionally mimic mammalian estrogens and show potential benefits for human health. The …

Phytoestrogens

RA Dixon - Annu. Rev. Plant Biol., 2004 - annualreviews.org
▪ Abstract Collectively, plants contain several different families of natural products among
which are compounds with weak estrogenic or antiestrogenic activity toward mammals …

Anthraquinones and derivatives from marine-derived fungi: Structural diversity and selected biological activities

M Fouillaud, M Venkatachalam, E Girard-Valenciennes… - Marine drugs, 2016 - mdpi.com
Anthraquinones and their derivatives constitute a large group of quinoid compounds with
about 700 molecules described. They are widespread in fungi and their chemical diversity …

Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent

G Srinivas, S Babykutty… - Medicinal research …, 2007 - Wiley Online Library
Anthraquinones represent a large family of compounds having diverse biological properties.
Emodin (1, 3, 8‐trihydroxy‐6‐methylanthraquinone) is a naturally occurring anthraquinone …

Environmental oestrogens, cosmetics and breast cancer

PD Darbre - Best practice & research clinical endocrinology & …, 2006 - Elsevier
The established role of oestrogen in the development and progression of breast cancer
raises questions concerning a potential contribution from the many chemicals in the …

Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway

YT Su, HL Chang, SK Shyue, SL Hsu - Biochemical pharmacology, 2005 - Elsevier
Emodin, a natural anthraquinone derivative isolated from Rheum palmatum L., has been
reported to exhibit anti-cancer effect on several human cancers such as liver cancers and …

Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway

R Huang, S Sakamuru, MT Martin, DM Reif… - Scientific reports, 2014 - nature.com
The US Tox21 program has screened a library of approximately 10,000 (10K) environmental
chemicals and drugs in three independent runs for estrogen receptor alpha (ERα) agonist …