Exosomes and cancer-Diagnostic and prognostic biomarkers and therapeutic vehicle

X Wang, L Tian, J Lu, IOL Ng - Oncogenesis, 2022 - nature.com
Exosomes belong to a subpopulation of extracellular vesicles secreted by the dynamic
multistep endocytosis process and carry diverse functional molecular cargoes, including …

[HTML][HTML] Extracellular vesicles: exosomes and microvesicles, integrators of homeostasis

PD Stahl, G Raposo - Physiology, 2019 - journals.physiology.org
Abstract Extracellular vesicles (EVs), cell-derived membrane structures, are secreted after
fusion of endosomes with the plasma membrane (exosomes) or shed from the plasma …

Tumor-derived exosomes, myeloid-derived suppressor cells, and tumor microenvironment

X Tian, H Shen, Z Li, T Wang, S Wang - Journal of hematology & oncology, 2019 - Springer
Plenty of immune cells infiltrate into the tumor microenvironment (TME) during tumor
progression, in which myeloid-derived suppressor cells (MDSCs) represent a …

Desmosomal cadherins in health and disease

M Hegazy, AL Perl, SA Svoboda… - Annual Review of …, 2022 - annualreviews.org
Desmosomal cadherins are a recent evolutionary innovation that make up the adhesive core
of highly specialized intercellular junctions called desmosomes. Desmosomal cadherins …

Biogenesis, membrane trafficking, functions, and next generation nanotherapeutics medicine of extracellular vesicles

S Gurunathan, MH Kang, M Qasim… - International Journal of …, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous group of membrane-limited vesicles and
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …

HSP‐enriched properties of extracellular vesicles involve survival of metastatic oral cancer cells

K Ono, T Eguchi, C Sogawa… - Journal of cellular …, 2018 - Wiley Online Library
Cancer cells often secrete extracellular vesicles (EVs) that carry heat shock proteins (HSPs)
with roles in tumor progression. Oral squamous cell carcinoma (OSCC) belongs to head and …

The role of cancer-associated fibroblasts and extracellular vesicles in tumorigenesis

I Shoucair, F Weber Mello, J Jabalee, S Maleki… - International Journal of …, 2020 - mdpi.com
Extracellular vesicles (EVs) play a key role in the communication between cancer cells and
stromal components of the tumor microenvironment (TME). In this context, cancer cell …

Extracellular vesicles in cancer diagnostics and therapeutics

A Shehzad, SU Islam, R Shahzad, S Khan… - Pharmacology & …, 2021 - Elsevier
Cancer promotion, development, and malignant transformation is greatly influenced by cell-
to-cell interactions in a complex tissue microenvironment. Cancer and stromal cells secrete …

The role of extracellular vesicles from different origin in the microenvironment of head and neck cancers

C Xie, N Ji, Z Tang, J Li, Q Chen - Molecular cancer, 2019 - Springer
The proliferation and metastasis ability of tumors are mediate by the" mutual dialogue"
between cells in the tumor microenvironment (TME). Extracellular vesicles (EVs), mainly …

Exosomal microRNAs (exoMIRs): micromolecules with macro impact in oral cancer

R Dhar, S Mallik, A Devi - 3 Biotech, 2022 - Springer
Exosomes are a sub-population of extracellular vesicles. It is released from all types of cells
and are observed to be involved in cellular communications. It contains DNA, RNA, proteins …