Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1

MG Dans, C Boulet, GM Watson, W Nguyen… - Nature …, 2024 - nature.com
With resistance to most antimalarials increasing, it is imperative that new drugs are
developed. We previously identified an aryl acetamide compound, MMV006833 (M-833) …

Aryl amino acetamides prevent the development of Plasmodium falciparum rings via inhibition of the lipid transfer protein PfSTART1

MG Dans, C Boulet, GM Watson, W Nguyen… - bioRxiv, 2023 - biorxiv.org
With resistance to most antimalarials increasing, it is imperative that new antimalarial drugs
are developed to replace or complement front-line artemisinin therapies. We previously …