Metabolic abnormalities and obesity's impact on the risk for developing preeclampsia

FT Spradley - American Journal of Physiology-Regulatory …, 2017 - journals.physiology.org
Preeclampsia (PE), a hypertensive disorder of pregnancy, is increasing as a major
contributor to perinatal and long-term morbidity of mother and offspring. PE is thought to …

Increased risk for the development of preeclampsia in obese pregnancies: weighing in on the mechanisms

FT Spradley, AC Palei… - American Journal of …, 2015 - journals.physiology.org
Preeclampsia (PE) is a pregnancy-specific disorder typically presenting as new-onset
hypertension and proteinuria. While numerous epidemiological studies have demonstrated …

[HTML][HTML] Evaluation of sFlt-1/PlGF ratio for predicting and improving clinical management of pre-eclampsia: Experience in a specialized perinatal care center

H Caillon, C Tardif, E Dumontet… - Annals of laboratory …, 2018 - synapse.koreamed.org
Background Management of pregnant women at high risk of pre-eclampsia (PE) requires
frequent monitoring, with referral to specialized perinatal care centers. Reliable tests are …

Blood biomarkers to predict the onset of pre-eclampsia: A systematic review and meta-analysis

M Danielli, RC Thomas, CL Gillies, J Hu, K Khunti… - Heliyon, 2022 - cell.com
Pre-eclampsia is one of the most common pregnancy complications, and a major cause of
fetal and maternal morbidity and mortality globally. Diagnosis currently takes place in the …

Clinical and biochemical factors associated with preeclampsia in women with obesity

MC Vieira, L Poston, E Fyfe, A Gillett, LC Kenny… - …, 2017 - Wiley Online Library
Objective To compare early pregnancy clinical and biomarker risk factors for later
development of preeclampsia between women with obesity (body mass index, BMI≥ 30 …

Obesity phenotype induced by high-fat diet leads to maternal-fetal constraint, placental inefficiency, and fetal growth restriction in mice

APV Sanches, JL de Oliveira, MS Ferreira… - The Journal of …, 2022 - Elsevier
The aim of this study was to investigate certain parameters regarding the maternal-fetal
outcomes in a diet-induced obesity model. Obese, glucose-intolerant females who were …

Increased serum iron levels in pregnant women with preeclampsia: a meta-analysis of observational studies

JX Liu, D Chen, MX Li, Y Hua - Journal of Obstetrics and …, 2019 - Taylor & Francis
Our study aimed to investigate whether the serum iron levels in patients with preeclampsia
were higher than in healthy pregnant women and to evaluate potential heterogeneities. We …

Serum biomarkers combined with uterine artery Doppler in prediction of preeclampsia

L Li, Y Zheng, Y Zhu, J Li - … and therapeutic medicine, 2016 - spandidos-publications.com
First-trimester screening may be a major advantage over a second-trimester approach since
it opens prospects for early and more efficient interventions. The aim of the current study was …

First trimester uterine artery Doppler, sFlt-1 and PlGF to predict preeclampsia in a high-risk population

C Diguisto, E Piver, AL Gouge, F Eboue… - The Journal of …, 2017 - Taylor & Francis
Objective: The study aims to evaluate the accuracy of combining uterine artery Doppler
(UAD), PlGF and sFlt-1 in the first trimester for preeclampsia screening. Methods …

Negative association between serum adropin and hypertensive disorders complicating pregnancy

D Lin, J Yong, S Ni, W Ou, X Tan - Hypertension in Pregnancy, 2019 - Taylor & Francis
Objective: Study the association of adropin and hypertensive disorders complicating
pregnancy (HDCP). Methods: Patients with HDCP were matched with normotensive women …