1, 2, 3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships
Z Xu, SJ Zhao, Y Liu - European journal of medicinal chemistry, 2019 - Elsevier
Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …
resistance associated with the currently used anticancer agents create an urgent need to …
Electrochemical arylation reaction
SR Waldvogel, S Lips, M Selt, B Riehl… - Chemical …, 2018 - ACS Publications
Arylated products are found in various fields of chemistry and represent essential entities for
many applications. Therefore, the formation of this structural feature represents a central …
many applications. Therefore, the formation of this structural feature represents a central …
Coumarin: A natural, privileged and versatile scaffold for bioactive compounds
A Stefanachi, F Leonetti, L Pisani, M Catto, A Carotti - Molecules, 2018 - mdpi.com
Many naturally occurring substances, traditionally used in popular medicines around the
world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal …
world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal …
Recent advancements of coumarin-based anticancer agents: An up-to-date review
T Al-Warhi, A Sabt, EB Elkaeed, WM Eldehna - Bioorganic Chemistry, 2020 - Elsevier
Heading the list of the critical health-related issues worldwide, cancer continues to be a one
of the most serious life-threatening diseases. The rate of cancer-related mortality is at …
of the most serious life-threatening diseases. The rate of cancer-related mortality is at …
Antibacterial activities with the structure-activity relationship of coumarin derivatives
The development of drug-resistant bacteria, as well as multidrug-resistant pathogens related
to substantial mortality, is an important global health threat. The wide range of biological …
to substantial mortality, is an important global health threat. The wide range of biological …
Coumarin-containing hybrids and their anticancer activities
L Zhang, Z Xu - European Journal of Medicinal Chemistry, 2019 - Elsevier
Cancer is the second leading cause of death worldwide, and it results in around 9 million
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …
Anticancer potential of coumarin and its derivatives
N Bhattarai, AA Kumbhar, YR Pokharel… - Mini Reviews in …, 2021 - ingentaconnect.com
Coumarins are found in higher plants like Rutaceae and Umbelliferae and essential oils of
cinnamon bark, cassia leaf, and lavender oil. Coumarin compounds show different …
cinnamon bark, cassia leaf, and lavender oil. Coumarin compounds show different …
Biological importance of structurally diversified chromenes
Compounds incorporating the chromene scaffold are largely present in natural products and
display a wide variety of biological activities. Their low toxicity combined to the broad …
display a wide variety of biological activities. Their low toxicity combined to the broad …
Synthetic heterocyclic candidates as promising α-glucosidase inhibitors: An overview
M Dhameja, P Gupta - European journal of medicinal chemistry, 2019 - Elsevier
Abstract α-Glucosidase enzyme inhibition is an effective therapeutic decorum in the
treatment of type 2 diabetes mellitus. Since 1990, three α-glucosidase inhibitors are known …
treatment of type 2 diabetes mellitus. Since 1990, three α-glucosidase inhibitors are known …
Synthesis of biologically active molecules through multicomponent reactions
Focusing on the literature progress since 2002, the present review explores the highly
significant role that multicomponent reactions (MCRs) have played as a very important tool …
significant role that multicomponent reactions (MCRs) have played as a very important tool …