Antimicrobial resistance in patients with COVID-19: a systematic review and meta-analysis

BJ Langford, M So, M Simeonova, V Leung, J Lo… - The Lancet …, 2023 - thelancet.com
Background Frequent use of antibiotics in patients with COVID-19 threatens to exacerbate
antimicrobial resistance. We aimed to establish the prevalence and predictors of bacterial …

Ventilator-associated pneumonia among SARS-CoV-2 acute respiratory distress syndrome patients

J Fumagalli, M Panigada, M Klompas… - Current opinion in …, 2022 - journals.lww.com
Covid-19 patients who require mechanical ventilation for ARDS have a high risk (> 50%) of
developing VAP, most commonly because of Gram-negative bacteria. Further work is …

Bacterial superinfection pneumonia in patients mechanically ventilated for COVID-19 pneumonia

CO Pickens, CA Gao, MJ Cuttica, SB Smith… - American journal of …, 2021 - atsjournals.org
Rationale: Current guidelines recommend patients with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) pneumonia receive empirical antibiotics for suspected …

Profiling the dysregulated immune response in sepsis: overcoming challenges to achieve the goal of precision medicine

S Cajander, M Kox, BP Scicluna… - The Lancet …, 2024 - thelancet.com
Sepsis is characterised by a dysregulated host immune response to infection. Despite
recognition of its significance, immune status monitoring is not implemented in clinical …

Community-acquired bacterial coinfections and COVID-19

MJ Patton, A Gaggar, M Might… - Physiological …, 2024 - journals.physiology.org
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the 29
causative pathogen of Coronavirus disease 2019 (COVID-19), has resulted in over 650 30 …

Antibiotics use in COVID-19 patients: a systematic literature review

G Granata, F Schiavone, G Pipitone, F Taglietti… - Journal of Clinical …, 2022 - mdpi.com
The issue of bacterial infections in COVID-19 patients has received increasing attention
among scientists. Antibiotics were widely prescribed during the early phase of the pandemic …

Epidemiology, risk factors and prognosis of ventilator-associated pneumonia during severe COVID-19: Multicenter observational study across 149 European Intensive …

M Garnier, JM Constantin, N Heming, L Camous… - … Critical Care & Pain …, 2023 - Elsevier
Background COVID-19 patients requiring mechanical ventilation are particularly at risk of
developing ventilator-associated pneumonia (VAP). Risk factors and the prognostic impact …

Bacterial coinfections contribute to severe COVID-19 in winter

H Fan, L Zhou, J Lv, S Yang, G Chen, X Liu, C Han… - Cell Research, 2023 - nature.com
Dear Editor, Although most cases of COVID-19 caused by SARS-CoV-2 Omicron variants
are mild or asymptomatic worldwide, coinfection with SARS-CoV-2 and other respiratory …

Ventilator-associated pneumonia in critically ill patients with COVID-19 infection: a narrative review

S Boyd, S Nseir, A Rodriguez… - ERJ open …, 2022 - Eur Respiratory Soc
COVID pneumonitis can cause patients to become critically ill. They may require intensive
care and mechanical ventilation. Ventilator-associated pneumonia (VAP) is a concern. This …

Respiratory multiplex PCR and procalcitonin to reduce antibiotic exposure in severe SARS-CoV-2 pneumonia: A multicentre randomized controlled trial

M Fartoukh, S Nseir, B Mégarbane, Y Cohen… - Clinical Microbiology …, 2023 - Elsevier
Objectives We aimed at assessing the efficacy and safety on antibiotic exposure of a
strategy combining a respiratory multiplex PCR (mPCR) with enlarged panel and daily …