Development of a multicompartment permeability‐limited lung PBPK model and its application in predicting pulmonary pharmacokinetics of antituberculosis drugs
Achieving sufficient concentrations of antituberculosis (TB) drugs in pulmonary tissue at the
optimum time is still a challenge in developing therapeutic regimens for TB. A …
optimum time is still a challenge in developing therapeutic regimens for TB. A …
Clinical use of biomarkers of survival in pulmonary fibrosis
M Thomeer, JC Grutters, WA Wuyts, S Willems… - Respiratory …, 2010 - Springer
Background Biologic predictors or biomarkers of survival in pulmonary fibrosis with a worse
prognosis, more specifically in idiopathic pulmonary fibrosis would help the clinician in …
prognosis, more specifically in idiopathic pulmonary fibrosis would help the clinician in …
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R Kammoun, HB Saad - La Tunisie medicale, 2020 - latunisiemedicale.com
Objectif. The objective of this literature review is to gather all the LFT norms available for the
Tunisian population, as well as QDV questionnaires specific to chronic respiratory patients …
Tunisian population, as well as QDV questionnaires specific to chronic respiratory patients …
Establishing a hemoglobin adjustment for 129Xe gas exchange MRI and MRS
Purpose 129Xe MRI and MRS signals from airspaces, membrane tissues (M), and red blood
cells (RBCs) provide measurements of pulmonary gas exchange. However, 129Xe …
cells (RBCs) provide measurements of pulmonary gas exchange. However, 129Xe …
Airborne particulate matters induce thrombopoiesis from megakaryocytes through regulating mitochondrial oxidative phosphorylation
X Jin, H Yu, B Wang, Z Sun, Z Zhang, QS Liu… - Particle and Fibre …, 2021 - Springer
Background Although airborne fine particulate matter (PM) pollution has been demonstrated
as an independent risk factor for pulmonary and cardiovascular diseases, their currently …
as an independent risk factor for pulmonary and cardiovascular diseases, their currently …
Reference values of pulmonary diffusing capacity for nitric oxide in an adult population
Our objective was to create reference values for single-breath DLNO based on a sample of
non-smoking healthy males and females using a short breath-hold time. The sample …
non-smoking healthy males and females using a short breath-hold time. The sample …
Diffusing capacity for nitric oxide and carbon monoxide in patients with diffuse parenchymal lung disease and pulmonary arterial hypertension
I van der Lee, P Zanen, JC Grutters, RJ Snijder… - Chest, 2006 - Elsevier
Background The passage of carbon monoxide (CO) through the alveolocapillary membrane
and into the plasma and intraerythrocytic compartments determines the diffusing capacity of …
and into the plasma and intraerythrocytic compartments determines the diffusing capacity of …
Sarcoidosis. Disease progression based on radiological and functional course: Predictive factors
A Casal, J Suárez-Antelo, R Soto-Feijóo, L Ferreiro… - Heart & Lung, 2022 - Elsevier
Background Sarcoidosis is a multiorgan granulomatous disease with a variable course.
Oobjectives The purpose of this study is to identify the patients that are more likely to …
Oobjectives The purpose of this study is to identify the patients that are more likely to …
Improvement in lung diffusion by endothelin A receptor blockade at high altitude
C De Bisschop, JB Martinot… - Journal of applied …, 2012 - journals.physiology.org
Lung diffusing capacity has been reported variably in high-altitude newcomers and may be
in relation to different pulmonary vascular resistance (PVR). Twenty-two healthy volunteers …
in relation to different pulmonary vascular resistance (PVR). Twenty-two healthy volunteers …
Alveolar-membrane diffusing capacity improves in the morbidly obese after bariatric surgery
GS Zavorsky, DJ Kim, JL Sylvestre, NV Christou - Obesity surgery, 2008 - Springer
Background Morbidly obese individuals may have impaired alveolar-membrane diffusing
capacity (DmCO). The purpose of this study was to measure pulmonary diffusing capacity for …
capacity (DmCO). The purpose of this study was to measure pulmonary diffusing capacity for …