Expanding the Landscape of Noncanonical Amino Acids in RiPP Biosynthesis
BA Johnson, KA Clark, LB Bushin… - Journal of the …, 2024 - ACS Publications
Advancements in DNA sequencing technologies and bioinformatics have enabled the
discovery of new metabolic reactions from overlooked microbial species and metagenomic …
discovery of new metabolic reactions from overlooked microbial species and metagenomic …
Biosynthesis of the Azoxy Compound Azodyrecin from Streptomyces mirabilis P8-A2
Azoxy compounds are a distinctive group of bioactive secondary metabolites characterized
by a unique RN═ N+ (O–) R moiety. The azoxy moiety is present in various classes of …
by a unique RN═ N+ (O–) R moiety. The azoxy moiety is present in various classes of …
Maramycin, a cytotoxic isoquinolinequinone terpenoid produced through heterologous expression of a bifunctional indole prenyltransferase/tryptophan indole-lyase in …
Isoquinolinequinones represent an important family of natural alkaloids with profound
biological activities. Heterologous expression of a rare bifunctional indole prenyltransferase …
biological activities. Heterologous expression of a rare bifunctional indole prenyltransferase …
Dilarmycins A–C, Calcium-Dependent Lipopeptide Antibiotics with a Non-canonical Ca2+-Binding Motif
I Fernández-Pastor, FJ Ortiz-López… - Organic …, 2024 - ACS Publications
Genome analysis of strain Streptomyces sp. CA-278952 revealed a biosynthetic gene
cluster encoding a putative lipopeptide with a sequence containing an Asp-Gly-Glu-Ala …
cluster encoding a putative lipopeptide with a sequence containing an Asp-Gly-Glu-Ala …