Schizophrenia and autism: both shared and disorder-specific pathogenesis via perinatal inflammation?
Prenatal exposure to infection and subsequent inflammatory responses have been
implicated in the etiology of schizophrenia and autism. In this review, we summarize current …
implicated in the etiology of schizophrenia and autism. In this review, we summarize current …
Cytokine imbalance in schizophrenia. from research to clinic: potential implications for treatment
Cytokines are one of the most important components of the immune system. They
orchestrate the brain's response to infectious and other exogenous insults and are crucial …
orchestrate the brain's response to infectious and other exogenous insults and are crucial …
Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids
Due to an inability to ethically access developing human brain tissue as well as identify
prospective cases, early-arising neurodevelopmental and cell-specific signatures of …
prospective cases, early-arising neurodevelopmental and cell-specific signatures of …
Impaired regulatory T cell control of astroglial overdrive and microglial pruning in schizophrenia
F Corsi-Zuelli, B Deakin - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
It is widely held that schizophrenia involves an active process of peripheral inflammation that
induces or reflects brain inflammation with activation of microglia, the brain's resident …
induces or reflects brain inflammation with activation of microglia, the brain's resident …
Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer
R Tabares-Seisdedos, JLR Rubenstein - Molecular psychiatry, 2009 - nature.com
Defects in genetic and developmental processes are thought to contribute susceptibility to
autism and schizophrenia. Presumably, owing to etiological complexity identifying …
autism and schizophrenia. Presumably, owing to etiological complexity identifying …
Prenatal exposure to environmental insults and enhanced risk of developing Schizophrenia and Autism Spectrum Disorder: focus on biological pathways and …
N Cattane, J Richetto, A Cattaneo - Neuroscience & Biobehavioral …, 2020 - Elsevier
When considering neurodevelopmental disorders (NDDs), Schizophrenia (SZ) and Autism
Spectrum Disorder (ASD) are considered to be among the most severe in term of …
Spectrum Disorder (ASD) are considered to be among the most severe in term of …
Cytokine profile in first-episode psychosis, unaffected siblings and community-based controls: the effects of familial liability and childhood maltreatment
BackgroundInflammation is a possible biological mechanism underlying the association
between childhood maltreatment and psychosis. Previous investigations on this regard were …
between childhood maltreatment and psychosis. Previous investigations on this regard were …
Anti-inflammatory signaling in schizophrenia
U Meyer - Brain, behavior, and immunity, 2011 - Elsevier
A great deal of interest has been centered upon activated inflammatory processes in
schizophrenia and their contribution to disease-relevant brain and behavioral impairment. In …
schizophrenia and their contribution to disease-relevant brain and behavioral impairment. In …
Peripheral blood-based gene expression studies in schizophrenia: a systematic review
VV Wagh, P Vyas, S Agrawal, TA Pachpor… - Frontiers in …, 2021 - frontiersin.org
Schizophrenia is a disorder that is characterized by delusions, hallucinations, disorganized
speech or behavior, and socio-occupational impairment. The duration of observation and …
speech or behavior, and socio-occupational impairment. The duration of observation and …
Genome-wide expression analysis of peripheral blood identifies candidate biomarkers for schizophrenia
The aim of this study was to analyze gene expression in blood of patients with newly-
diagnosed schizophrenia during their first psychotic episode and subsequent remission …
diagnosed schizophrenia during their first psychotic episode and subsequent remission …