The dopamine hypothesis of autism spectrum disorder revisited: current status and future prospects

D Pavăl, IV Micluția - Developmental neuroscience, 2021 - karger.com
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. Despite intensive research, its …

[HTML][HTML] Neuroimaging genetics approaches to identify new biomarkers for the early diagnosis of autism spectrum disorder

S Nisar, M Haris - Molecular psychiatry, 2023 - nature.com
Autism-spectrum disorders (ASDs) are developmental disabilities that manifest in early
childhood and are characterized by qualitative abnormalities in social behaviors …

[HTML][HTML] Increased glutamate and glutamine levels and their relationship to astrocytes and dopaminergic transmissions in the brains of adults with autism

M Oya, K Matsuoka, M Kubota, J Fujino, S Tei… - Scientific Reports, 2023 - nature.com
Increased excitatory neuronal tones have been implicated in autism, but its mechanism
remains elusive. The amplified glutamate signals may arise from enhanced glutamatergic …

[HTML][HTML] Striatal dopamine synthesis capacity in autism spectrum disorder and its relation with social defeat: an [18F]-FDOPA PET/CT study

R Schalbroeck, FHP van Velden… - Translational …, 2021 - nature.com
Alterations in dopamine signalling have been implied in autism spectrum disorder (ASD),
and these could be associated with the risk of developing a psychotic disorder in ASD …

[HTML][HTML] Pathophysiological studies of monoaminergic neurotransmission systems in valproic acid-induced model of autism spectrum disorder

HY Kuo, FC Liu - Biomedicines, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex etiology.
The core syndromes of ASD are deficits in social communication and self-restricted interests …

Neural correlates of perceptual switching and their association with empathy and alexithymia in individuals with and without autism spectrum disorder

S Tei, T Itahashi, YY Aoki, M Kubota… - Journal of Psychiatric …, 2023 - Elsevier
Individuals with autism spectrum disorder (ASD) often show limited empathy (poor
recognition of others' emotions) and high alexithymia (poor recognition of own emotions and …

[HTML][HTML] Positron emission tomography in the neuroimaging of autism spectrum disorder: a review

Z Tan, H Wei, X Song, W Mai, J Yan, W Ye… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a basket term for neurodevelopmental disorders
characterized by marked impairments in social interactions, repetitive and stereotypical …

[HTML][HTML] The functional neural architecture of dysfunctional reward processing in autism

H Janouschek, HW Chase, RJ Sharkey, ZJ Peterson… - NeuroImage: Clinical, 2021 - Elsevier
Functional imaging studies have found differential neural activation patterns during reward-
paradigms in patients with autism spectrum disorder (ASD) compared to neurotypical …

[HTML][HTML] Attentional disengagement and the locus coeruleus–norepinephrine system in children with autism spectrum disorder

B Keehn, G Kadlaskar, S Bergmann… - Frontiers in integrative …, 2021 - frontiersin.org
Background Differences in non-social attentional functions have been identified as among
the earliest features that distinguish infants later diagnosed with autism spectrum disorder …

Measures of tonic and phasic activity of the locus coeruleus—norepinephrine system in children with autism spectrum disorder: An event‐related potential and …

Y Kim, G Kadlaskar, RMN Keehn, B Keehn - Autism Research, 2022 - Wiley Online Library
A growing body of research suggests that locus coeruleus‐norepinephrine (LC‐NE) system
may function differently in individuals with autism spectrum disorder (ASD). Understanding …