Mobile cognition: imaging the human brain in the 'real world'

M Stangl, SL Maoz, N Suthana - Nature Reviews Neuroscience, 2023 - nature.com
Cognitive neuroscience studies in humans have enabled decades of impactful discoveries
but have primarily been limited to recording the brain activity of immobile participants in a …

Cognition and dementia in older patients with epilepsy

A Sen, V Capelli, M Husain - Brain, 2018 - academic.oup.com
With advances in healthcare and an ageing population, the number of older adults with
epilepsy is set to rise substantially across the world. In developed countries the highest …

[HTML][HTML] Augmenting hippocampal–prefrontal neuronal synchrony during sleep enhances memory consolidation in humans

M Geva-Sagiv, EA Mankin, D Eliashiv, S Epstein… - Nature …, 2023 - nature.com
Memory consolidation during sleep is thought to depend on the coordinated interplay
between cortical slow waves, thalamocortical sleep spindles and hippocampal ripples, but …

Fast-specific fluorescent probes to visualize norepinephrine signaling pathways and its flux in the epileptic mice brain

H Yan, Y Wang, F Huo, C Yin - Journal of the American Chemical …, 2023 - ACS Publications
Norepinephrine (NE) is synthesized in the locus coeruleus and widely projected throughout
the brain and spinal cord. It regulates various actions and consciousness linked to a variety …

Enhancement-mode ion-based transistor as a comprehensive interface and real-time processing unit for in vivo electrophysiology

C Cea, GD Spyropoulos, P Jastrzebska-Perfect… - Nature materials, 2020 - nature.com
Bioelectronic devices must be fast and sensitive to interact with the rapid, low-amplitude
signals generated by neural tissue. They should also be biocompatible and soft, and should …

Human REM sleep recalibrates neural activity in support of memory formation

JD Lendner, N Niethard, BA Mander… - Science …, 2023 - science.org
The proposed mechanisms of sleep-dependent memory consolidation involve the overnight
regulation of neural activity at both synaptic and whole-network levels. Now, there is a lack …

Learning-enhanced coupling between ripple oscillations in association cortices and hippocampus

D Khodagholy, JN Gelinas, G Buzsáki - Science, 2017 - science.org
Consolidation of declarative memories requires hippocampal-neocortical communication.
Although experimental evidence supports the role of sharp-wave ripples in transferring …

[HTML][HTML] Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity

EC Rosenberg, S Chamberland, M Bazelot, ER Nebet… - Neuron, 2023 - cell.com
Summary Cannabidiol (CBD), a non-euphoric component of cannabis, reduces seizures in
multiple forms of pediatric epilepsies, but the mechanism (s) of anti-seizure action remain …

[HTML][HTML] Bidirectional prefrontal-hippocampal dynamics organize information transfer during sleep in humans

RF Helfrich, JD Lendner, BA Mander, H Guillen… - Nature …, 2019 - nature.com
How are memories transferred from short-term to long-term storage? Systems-level memory
consolidation is thought to be dependent on the coordinated interplay of cortical slow waves …

Brain-wide interactions during hippocampal sharp wave ripples

N Nitzan, R Swanson, D Schmitz… - Proceedings of the …, 2022 - National Acad Sciences
During periods of disengagement from the environment, transient population bursts, known
as sharp wave ripples (SPW-Rs), occur sporadically. While numerous experiments have …