MicroRNAs (miRNAs) play indispensable roles in posttranscriptional gene regulation. Their
cellular regulatory impact is determined not solely by their sheer number, which likely …

Proteins are released from cells by different secretory pathways. The secretory pathway via
the ER-Golgi route-realized by a signal sequence-is referred to as “classical secretion”. In …

The diaphragm is a crucial muscle involved in active inspiration and whole body
homeostasis. Previous biochemical, immunochemical and cell biological investigations …

Elevated levels of galectin-3 are associated with tumorigenesis. Its inhibition with high-
affinity carbohydrate ligands opens new therapeutic routes. Targeting of intracellular …

(1) Background: The atopic march is defined by the increased prevalence of allergic
diseases after atopic dermatitis onset. In fact, atopic dermatitis is believed to play an …

The level of microRNA (miR)‐431 was found to be markedly up‐regulated in intestinal tissue
of necrotizing enterocolitis (NEC). The objective of this study was to identify the target gene …

The present study focuses on the association between metabolic capacity and toxicity of the
natural occurring flavonoid nevadensin in vitro. Human colon (HT29), liver (HepG2) and …

Background Duchenne muscular dystrophy is a highly complex multi-system disease
caused by primary abnormalities in the membrane cytoskeletal protein dystrophin. Besides …

BACKGROUND No agents that are specifically neuroprotective are currently approved to
emergently treat patients with traumatic brain injury (TBI). The histone deacetylase inhibitor …

Giardia intestinalis is a unicellular protozoan parasite that infects the small intestines of
humans and animals. Giardiasis, the disease caused by the parasite, occurs globally across …