Consumers highly appreciate table grapes for their pleasant sensory attributes and as good
sources of nutritional and functional compounds. This explains the rising market and global …

Nitrogen is one of the most important essential nutrient sources for biogenic activities.
Regulation of nitrogen metabolism in microorganisms is complicated and elaborate. For this …

Microbial biosynthesis of plant natural products (PNPs) can facilitate access to valuable
medicinal compounds and derivatives. Such efforts are challenged by metabolite transport …

Proteins are secreted from eukaryotic cells by several mechanisms besides the well-
characterized classical secretory system. Proteins destined to enter the classical secretory …

Exosomes contain multiple bioactive molecules and maintain the connection between cells.
Recent advances in exosome-based therapeutics have witnessed unprecedented …

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron degenerative disease. ALS-
affected motor neurons exhibit aberrant localization of a nuclear RNA binding protein, TDP …

TRAPP is a highly conserved modular multi-subunit protein complex. Originally identified as
a “transport protein particle” with a role in endoplasmic reticulum-to-Golgi transport, its …

Genetic elements are foundational in synthetic biology serving as vital building blocks. They
enable programming host cells for efficient production of valuable chemicals and …

Early endosomes, also called sorting endosomes, are known to mature into late endosomes
via the Rab5-mediated endolysosomal trafficking pathway. Thus, early endosome existence …

The cell interior is packed with macromolecules of mesoscale size, and this crowded milieu
significantly influences cellular physiology. Cellular stress responses almost universally lead …