Abstract The phosphatidylinositol 3‑kinase (PI3K)/protein kinase B (AKT) signaling pathway
is involved in the regulation of multiple cellular physiological processes by activating …

Introduction: The advent of high throughput technologies capable of comprehensive
analysis of genes, transcripts, proteins and other significant biological molecules has …

BACKGROUND Cervical cancer is the second leading cause of cancer deaths among
women worldwide. The objective of this study was to describe the most common oncogenic …

Human papillomavirus (HPV)-induced cancers will remain a significant clinical challenge for
decades. Thus, the development of novel treatment strategies is urgently required, which …

Cervical cancer is a common gynecological cancer and a leading cause of cancer‐related
death in women globally. There is a need for the identification of prognostic and predictive …

Background: The phosphoinositide 3-kinase (PI3K)/Akt signalling pathway appears to be a
key regulator in cervical carcinogenesis. However, the downstream regulatory mechanism of …

Human papillomaviruses (HPVs) are small double‐stranded circular DNA viruses with 8 kb
genomes. So far, more than 150 HPVs have been identified, and 12 types of HPVs have …

Cervical cancer is a public health issue in developing countries. Although the Pap smear
and colposcopy remain the major strategies for detection, most cases are diagnosed in the …

OBJECTIVE: Mutational activation of PIK3CA is associated with poor prognosis in patients
with solid tumors, and may predict favorable response to PI3K/AKT/mTOR pathway …

Background Cervical cancer (CC) is one of the most common cancers among females
worldwide. Spindle and kinetochore-associated complex subunit 3 (SKA3), located on …