Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

SY Lunt, MG Vander Heiden - Annual review of cell and …, 2011 - annualreviews.org
Warburg's observation that cancer cells exhibit a high rate of glycolysis even in the presence
of oxygen (aerobic glycolysis) sparked debate over the role of glycolysis in normal and …

Machine learning and radiology

S Wang, RM Summers - Medical image analysis, 2012 - Elsevier
In this paper, we give a short introduction to machine learning and survey its applications in
radiology. We focused on six categories of applications in radiology: medical image …

Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging

M Law, S Yang, H Wang, JS Babb… - American journal …, 2003 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Sensitivity, positive predictive value (PPV), and negative
predictive value (NPV) of conventional MR imaging in predicting glioma grade are not high …

The biogenesis and functions of lipid bodies in animals, plants and microorganisms

DJ Murphy - Progress in lipid research, 2001 - Elsevier
What are lipid bodies? One of the problems in answering this apparently simple question is
that these macromolecular proteolipid assemblies can be relatively heterogeneous with …

Metabolic profiles of cancer cells

JL Griffin, JP Shockcor - Nature reviews cancer, 2004 - nature.com
In the post-genomic era, several profiling tools have been developed to provide a more
comprehensive picture of tumour development and progression. The global analysis of …

A constrained least‐squares approach to the automated quantitation of in vivo 1H magnetic resonance spectroscopy data

M Wilson, G Reynolds, RA Kauppinen… - Magnetic resonance …, 2011 - Wiley Online Library
Abstract Totally Automatic Robust Quantitation in NMR (TARQUIN), a new method for the
fully automatic analysis of short echo time in vivo 1H Magnetic resonance spectroscopy is …

Imaging of brain tumors: MR spectroscopy and metabolic imaging

A Horská, PB Barker - Neuroimaging Clinics, 2010 - neuroimaging.theclinics.com
Localized proton magnetic resonance spectroscopy (MRS) of the human brain, first reported
more than 20 years ago, 1–3 is a mature methodology that is used clinically in many medical …

High-grade gliomas and solitary metastases: differentiation by using perfusion and proton spectroscopic MR imaging

M Law, S Cha, EA Knopp, G Johnson, J Arnett, AW Litt - Radiology, 2002 - pubs.rsna.org
PURPOSE: To determine whether perfusion-weighted and proton spectroscopic MR
imaging can be used to differentiate high-grade primary gliomas and solitary metastases on …

Lipid and metabolite profiles of human brain tumors by desorption electrospray ionization-MS

AK Jarmusch, V Pirro, Z Baird… - Proceedings of the …, 2016 - National Acad Sciences
Examination of tissue sections using desorption electrospray ionization (DESI)-MS revealed
phospholipid-derived signals that differ between gray matter, white matter, gliomas …

Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy

FA Howe, SJ Barton, SA Cudlip… - … in Medicine: An …, 2003 - Wiley Online Library
Proton spectroscopy can noninvasively provide useful information on brain tumor type and
grade. Short‐(30 ms) and long‐(136 ms) echo time (TE) 1H spectra were acquired from …