Colchicine for COVID-19: targeting NLRP3 inflammasome to blunt hyperinflammation

A Bonaventura, A Vecchié, L Dagna, F Tangianu… - Inflammation …, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is capable of inducing the
activation of NACHT, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) …

Drug-induced liver injury in COVID-19 patients: a systematic review

F Sodeifian, ZS Seyedalhosseini, N Kian… - Frontiers in …, 2021 - frontiersin.org
Introduction: The severity of COVID-19 may be correlated with the risk of liver injury
development. An increasing number of studies indicate that degrees of hepatotoxicity has …

Pre-admission glucagon-like peptide-1 receptor agonist (GLP-1RA) and mortality from coronavirus disease 2019 (Covid-19): A systematic review, meta-analysis, and …

TI Hariyanto, D Intan, JE Hananto, C Putri… - diabetes research and …, 2021 - Elsevier
Aims GLP-1RA has many beneficial properties, including anti-inflammatory, anti-
obesogenic, pulmonary protective effects as well as beneficial impact on gut microbiome …

Ivermectin and outcomes from Covid‐19 pneumonia: a systematic review and meta‐analysis of randomized clinical trial studies

TI Hariyanto, DA Halim, J Rosalind, C Gunawan… - 2022 - Wiley Online Library
Ivermectin is an FDA‐approved drug for a parasitic disease that has broad antiviral activity.
This study aims to analyse the efficacy of ivermectin in improving the Covid‐19 outcomes …

Efficacy of COVID-19 treatments: a Bayesian network meta-analysis of randomized controlled trials

C Zhang, H Jin, YF Wen, G Yin - Frontiers in Public Health, 2021 - frontiersin.org
Background: We provided a comprehensive evaluation of efficacy of available treatments for
coronavirus disease 2019 (COVID-19). Methods: We searched for candidate COVID-19 …

Acute respiratory distress syndrome and COVID-19: A literature review

M Hussain, S Khurram Syed, M Fatima… - Journal of …, 2021 - Taylor & Francis
Acute respiratory distress syndrome (ARDS) is an overwhelming inflammatory disorder of
the lung due to direct and indirect insults to the lungs. ARDS is characterized by increased …

Vitamin D supplementation and Covid‐19 outcomes: a systematic review, meta‐analysis and meta‐regression

TI Hariyanto, D Intan, JE Hananto, H Harapan… - 2022 - Wiley Online Library
Vitamin D has many protective properties and potential role against acute lung injury. Low
serum vitamin D is associated with high risk of pneumonia and development of acute …

Janus kinase (JAK)-inhibitors and coronavirus disease 2019 (Covid-19) outcomes: a systematic review and meta-analysis

RY Limen, R Sedono, A Sugiarto… - Expert Review of Anti …, 2022 - Taylor & Francis
Background Currently, JAK-inhibitors are repurposed for therapy of Covid-19 because of
their ability in restraining immune response, yet the corroboration regarding their advantage …

Delirium is a good predictor for poor outcomes from coronavirus disease 2019 (COVID-19) pneumonia: a systematic review, meta-analysis, and meta-regression

TI Hariyanto, C Putri, JE Hananto, J Arisa… - Journal of psychiatric …, 2021 - Elsevier
Aim Delirium is a common presenting symptom among older patients. Patients who
presented with delirium may have a higher morbidity and mortality rate due to older age …

Coronavirus disease 2019 (Covid-19) outcomes in patients with sarcopenia: a meta-analysis and meta-regression

YMT Siahaan, V Hartoyo, TI Hariyanto… - Clinical nutrition …, 2022 - Elsevier
Background Sarcopenia has been associated with patients' poor quality of life, disability,
and hospitalization. As of today, evidence that highlights the association between …