Mechanism and biological role of Dnmt2 in nucleic acid methylation
A Jeltsch, A Ehrenhofer-Murray, TP Jurkowski… - RNA biology, 2017 - Taylor & Francis
ABSTRACT A group of homologous nucleic acid modification enzymes called Dnmt2,
Trdmt1, Pmt1, DnmA, and Ehmet in different model organisms catalyze the transfer of a …
Trdmt1, Pmt1, DnmA, and Ehmet in different model organisms catalyze the transfer of a …
[HTML][HTML] The emerging field of epitranscriptomics in neurodevelopmental and neuronal disorders
MT Angelova, DG Dimitrova, N Dinges… - … in bioengineering and …, 2018 - frontiersin.org
Analogous to DNA methylation and histone modifications, RNA modifications represent a
novel layer of regulation of gene expression. The dynamic nature and increasing number of …
novel layer of regulation of gene expression. The dynamic nature and increasing number of …
RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage
M Schaefer, T Pollex, K Hanna, F Tuorto… - Genes & …, 2010 - genesdev.cshlp.org
Dnmt2 proteins are the most conserved members of the DNA methyltransferase enzyme
family, but their substrate specificity and biological functions have been a subject of …
family, but their substrate specificity and biological functions have been a subject of …
Solving the Dnmt2 enigma
M Schaefer, F Lyko - Chromosoma, 2010 - Springer
Dnmt2 is a member of the animal DNA methyltransferase family of enzymes. While the role
of other Dnmt proteins has been extensively characterized, comparably little is known about …
of other Dnmt proteins has been extensively characterized, comparably little is known about …
Characterization of the dual role of Plasmodium falciparum DNA methyltransferase in regulating transcription and translation
AB Lucky, C Wang, X Li, A Chim-Ong… - Nucleic acids …, 2023 - academic.oup.com
DNA modifications are critical in fine-tuning the biological processes in model organisms.
However, the presence of cytosine methylation (5mC) and the function of the putative DNA …
However, the presence of cytosine methylation (5mC) and the function of the putative DNA …
[HTML][HTML] Prolonged effects of silver nanoparticles on p53/p21 pathway-mediated proliferation, DNA damage response, and methylation parameters in HT22 …
J Mytych, J Zebrowski, A Lewinska, M Wnuk - Molecular neurobiology, 2017 - Springer
It is widely accepted that silver nanoparticles (AgNPs) are toxic to biological systems.
However, little is known about their actions at molecular level and the cytophysiological …
However, little is known about their actions at molecular level and the cytophysiological …
[HTML][HTML] TRDMT1-mediated RNA C-5 methylation as a novel target in anticancer therapy
A Lewinska, J Adamczyk-Grochala, M Wnuk - Biochimica et Biophysica …, 2023 - Elsevier
Affected landscape of RNA modifications is frequently observed in different cancer cells that
can be associated with the development of cancer cell phenotypic traits such as sustained …
can be associated with the development of cancer cell phenotypic traits such as sustained …
Mapping and significance of the mRNA methylome
Internal methylation of eukaryotic mRNAs in the form of N6‐methyladenosine (m6A) and 5‐
methylcytidine (m5C) has long been known to exist, but progress in understanding its role …
methylcytidine (m5C) has long been known to exist, but progress in understanding its role …
[HTML][HTML] Reduced levels of methyltransferase DNMT2 sensitize human fibroblasts to oxidative stress and DNA damage that is accompanied by changes in proliferation …
A Lewinska, J Adamczyk-Grochala, E Kwasniewicz… - Redox Biology, 2018 - Elsevier
Methyltransferase DNMT2 is suggested to be involved in the regulation of numerous
processes, however its biological significance and underlying molecular mechanisms …
processes, however its biological significance and underlying molecular mechanisms …
TRDMT1 exhibited protective effects against LPS‐induced inflammation in rats through TLR4‐NF‐κB/MAPK‐TNF‐α pathway
Z Li, X Qi, X Zhang, L Yu, L Gao, W Kong… - Animal Models and …, 2022 - Wiley Online Library
Background Inflammation is a complex physiological and pathological process. Although
many types of inflammation are well characterized, their physiological functions are largely …
many types of inflammation are well characterized, their physiological functions are largely …