Application of Box–Behnken design combined response surface methodology to optimize HPLC and spectrophotometric techniques for quantifying febuxostat in …

SM Haque, H Rahman, N Rahman, SNH Azmi… - Microchemical …, 2023 - Elsevier
This study applied an optimized Box-Behnken Design (BBD) to develop visible
spectrophotometry and a high-performance liquid chromatography (HPLC) method for …

Two different synchronous spectrofluorimetric approaches for simultaneous determination of febuxostat and ibuprofen

G Magdy, F Belal, AM Abdel-Megied… - Royal Society …, 2021 - royalsocietypublishing.org
Two green, simple and sensitive synchronous spectrofluorimetric methods were developed
for the first time for the simultaneous estimation of febuxostat (FEB) and ibuprofen (IBU) …

Synthesis of some new nanoparticles mixed metal complexes of febuxostat in presence of 2, 2′-bipyridine: Characterization, DFT, antioxidant and molecular docking …

LM Abbass, SA Sadeek, MAER Aziz, WA Zordok… - Journal of Molecular …, 2023 - Elsevier
Abstract New Mn (II), Fe (III), Co (II), and Ni (II) complexes with urate lowing drug febuxostat
(FEB) and 2, 2′-bipyridine (Bipy) were designed and depicted. Elemental analysis, molar …

Mixed ligand 4‑hydroxy acetanilide-febuxostat complexes of Co (II),-Ni (II), Cu (II) and Zr (IV): Synthesis, structural characterization, DFT calculations, antibacterial …

LM Abbass, SA Sadeek, WA Zordok… - Journal of Molecular …, 2024 - Elsevier
The synthesized mixed ligand metal complexes were achieved by a combination of
febuxostat (2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid)(FEB) and …

Micelle-enhanced conventional and synchronous spectrofluorimetric methods for the simultaneous determination of lesinurad and febuxostat: Application to human …

G Magdy, FF Belal, AM Abdel-Megied… - Spectrochimica Acta Part …, 2021 - Elsevier
A simple synchronous spectrofluorimetric method was developed for simultaneous
determination of lesinurad and febuxostat. The investigated drugs were measured at 294 …

A review on: Analysis of certain drugs used in gout treatment

NM Hosny, NN Atia, SM El-Gizawy - Microchemical Journal, 2019 - Elsevier
A comprehensive review with 129 references for the analysis of commonly prescribed
antigout drugs is presented. The review covers most of the methods described for the …

Facile micelle-enhanced spectrofluorimetric method for picogram level determination of febuxostat; application in tablets and in real human plasma

NN Atia, SM El-Gizawy, NM Hosny - Microchemical Journal, 2019 - Elsevier
Ultrasensitive, specific, rapid and economic spectrofluorimetric method was developed and
validated for determination of a selective xanthine oxidase inhibitor; Febuxostat (FBX) in …

Fabrication of ZIF-71/Fe 3 O 4/polythionine nanoarray-functionalized carbon cotton cloth for simultaneous extraction and quantitation of febuxostat and diclofenac

Y Sanaei, M Zeeb, SS Homami, A Monzavi… - RSC …, 2021 - pubs.rsc.org
A sustainable hybrid material based on carbonized cotton cloth/zeolite imidazolate
framework-71/Fe3O4/polythionine (CC/ZIF-71/Fe3O4/PTh) was synthesized and applied in …

Multi-spectroscopic assay methods for concurrent determination of recent anti-gout combination, a comparative study

NA Abdallah, ME Fathy, MM Tolba… - … Acta Part A: Molecular …, 2023 - Elsevier
Recently, Chemometric calibration methods in spectrophotometric analysis are achieving
significant attention in the quality control of resolving drug mixtures and pharmaceutical …

New approach for simultaneous analysis of commonly used antigout drugs by HPLC/UV method; application in pharmaceutical and biological analysis

NM Hosny, K Huddersman, SM El-Gizawy… - Microchemical Journal, 2019 - Elsevier
An innovative, simple, fast, specific and sensitive high performance liquid chromatographic
method with ultraviolet detection (HPLC/UV) was established and validated for simultaneous …