Pharmapolymers in the 21st century: Synthetic polymers in drug delivery applications
The administration of drugs, as a main challenge of pharmaceutical and medicinal
applications, has certainly benefited from the application of synthetic polymers. However …
applications, has certainly benefited from the application of synthetic polymers. However …
Poly (2‐oxazoline) s: a polymer class with numerous potential applications
R Hoogenboom - Angewandte Chemie International Edition, 2009 - Wiley Online Library
The living cationic ring‐opening polymerization of 2‐oxazolines has been studied in great
detail since its discovery in 1966. The versatility of this living polymerization method allows …
detail since its discovery in 1966. The versatility of this living polymerization method allows …
Poly (2‐oxazoline) s as Polymer Therapeutics
Abstract Poly (2‐oxazoline) s (POx) are currently discussed as an upcoming polymer
platform for biomaterials design and especially for polymer therapeutics. POx meet specific …
platform for biomaterials design and especially for polymer therapeutics. POx meet specific …
Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics
Synthetic methods in polymer chemistry have evolved tremendously during the last decade.
Nowadays more and more attention is devoted to the application of those tools in the …
Nowadays more and more attention is devoted to the application of those tools in the …
Polymerization of oxazolines
K Aoi, M Okada - Progress in polymer science, 1996 - Elsevier
Pergamon Page 1 Pergamon Prog. Polym. Sci., Vol. 21, 151-208, 1996 Copyright 0 1996
Elsevier Science Ltd Printed in Great Britain. All rights reserved. 0079%6700/96 $32.00 …
Elsevier Science Ltd Printed in Great Britain. All rights reserved. 0079%6700/96 $32.00 …
New amphipatic polymer-lipid conjugates forming long-circulating reticuloendothelial system-evading liposomes
MC Woodle, CM Engbers, S Zalipsky - Bioconjugate chemistry, 1994 - ACS Publications
The synthesis of POZ-lipid conjugates is shown in Scheme 1. The polymers were prepared
by methyl p-toluenesulfonate-initiated reactions of 2-methyl-and 2-ethyl-2-oxazolines …
by methyl p-toluenesulfonate-initiated reactions of 2-methyl-and 2-ethyl-2-oxazolines …
Double‐hydrophilic block copolymers: synthesis and application as novel surfactants and crystal growth modifiers
H Cölfen - Macromolecular Rapid Communications, 2001 - Wiley Online Library
Double‐hydrophilic block copolymers are a new class of amphiphilic molecules of rapidly
increasing importance with unique and fascinating properties potentially connecting …
increasing importance with unique and fascinating properties potentially connecting …
Evaluation of blood clearance rates and biodistribution of poly (2‐oxazoline)‐grafted liposomes
S Zalipsky, CB Hansen, JM Oaks… - Journal of …, 1996 - Wiley Online Library
Two amphipatic polymers of the poly (2‐oxazoline) family, poly (2‐methyl‐2‐
oxazoline)(PMOZ) and poly (2‐ethyl‐2‐oxazoline)(PEOZ), were synthesized with the …
oxazoline)(PMOZ) and poly (2‐ethyl‐2‐oxazoline)(PEOZ), were synthesized with the …
Polymer-drug conjugates: Design principles, emerging synthetic strategies and clinical overview
Adagen, an enzyme replacement treatment for adenosine deaminase deficiency, was the
first protein-polymer conjugate to be approved in early 1990 s. Post this regulatory approval …
first protein-polymer conjugate to be approved in early 1990 s. Post this regulatory approval …
Surface initiated living cationic polymerization of 2-oxazolines
A self-assembled monolayer on a planar gold substrate has been used to initiate the living
cationic ring-opening polymerization of 2-ethyl-2-oxazoline. The polymer chain end was …
cationic ring-opening polymerization of 2-ethyl-2-oxazoline. The polymer chain end was …