Chia seeds (Salvia hispanica L.): A therapeutic weapon in metabolic disorders

W Khalid, MS Arshad, A Aziz, MA Rahim… - Food Science & …, 2023 - Wiley Online Library
The growth of functional components containing agricultural foods is enhancing because
these components aid the human body against different chronic diseases. Currently, chia …

Ochratoxin A as an alarming health threat for livestock and human: A review on molecular interactions, mechanism of toxicity, detection, detoxification, and dietary …

WC Liu, K Pushparaj, A Meyyazhagan, VA Arumugam… - Toxicon, 2022 - Elsevier
Ochratoxin A (OTA) is a toxic metabolite produced by Aspergillus and Penicillium fungi
commonly found in raw plant sources and other feeds. This review comprises an extensive …

Melatonin mitigates aflatoxin B1‐induced liver injury via modulation of gut microbiota/intestinal FXR/liver TLR4 signaling axis in mice

S Liu, W Kang, X Mao, L Ge, H Du, J Li… - Journal of pineal …, 2022 - Wiley Online Library
Abstract Aflatoxin B1 (AFB1) is a widespread contaminant in foods and feedstuffs, and its
target organ is the liver. Melatonin (MT) has been shown to alleviate inflammation in organs …

Role and therapeutic potential of melatonin in various type of cancers

S Gurunathan, M Qasim, MH Kang… - OncoTargets and …, 2021 - Taylor & Francis
Cancer is a large group of diseases and the second leading cause of death worldwide.
Lung, prostate, colorectal, stomach, and liver cancers are the most common types of cancer …

Pineal gland tumors: a review

G Favero, F Bonomini, R Rezzani - Cancers, 2021 - mdpi.com
Simple Summary Pineal neoplasms are tumors with different and variable morphological,
histological, and radiological characteristics and, consequently different diagnosis and …

Melatonin and related compounds: antioxidant and anti-inflammatory actions

M Bantounou, J Plascevic, HF Galley - Antioxidants, 2022 - mdpi.com
Melatonin, an indoleamine derived from tryptophan and produced in the pineal gland and
other tissues [1, 2] is a potent antioxidant and inflammatory agent [1]. Specifically, the …

[HTML][HTML] Gestational cadmium exposure impairs placental angiogenesis via activating GC/GR signaling

XT Shi, HL Zhu, XF Xu, YW Xiong, LM Dai… - Ecotoxicology and …, 2021 - Elsevier
Gestational exposure to environmental Cd caused placental angiogenesis impairment and
fetal growth restriction (FGR). However, its mechanism remained unclear. This study was to …

Part-time cancers and role of melatonin in determining their metabolic phenotype

RJ Reiter, R Sharma, C Rodriguez, V Martin… - Life Sciences, 2021 - Elsevier
This brief review describes the association of the endogenous pineal melatonin rhythm with
the metabolic flux of solid tumors, particularly breast cancer. It also summarizes new …

The rationale for treating uveal melanoma with adjuvant melatonin: a review of the literature

A Hagström, R Kal Omar, PA Williams, G Stålhammar - BMC cancer, 2022 - Springer
Background Uveal melanoma is a rare form of cancer with high mortality. The incidence of
metastases is attributed to early seeding of micrometastases from the eye to distant organs …

Anti-drug resistance, anti-inflammation, and anti-proliferation activities mediated by melatonin in doxorubicin-resistant hepatocellular carcinoma: in vitro investigations

AR Hamed, SMM Yahya, HK Nabih - Naunyn-Schmiedeberg's Archives of …, 2023 - Springer
Hepatocellular carcinoma (HCC) is the major life-threatening primary liver malignancy in
both sexes all over the world. Unfortunately, the majority of patients are diagnosed at later …