Global trends in diabetes complications: a review of current evidence

JL Harding, ME Pavkov, DJ Magliano, JE Shaw… - Diabetologia, 2019 - Springer
In recent decades, large increases in diabetes prevalence have been demonstrated in
virtually all regions of the world. The increase in the number of people with diabetes or with …

Advanced glycation end products: new clinical and molecular perspectives

J Salazar, C Navarro, Á Ortega, M Nava… - International journal of …, 2021 - mdpi.com
Diabetes mellitus (DM) is considered one of the most massive epidemics of the twenty-first
century due to its high mortality rates caused mainly due to its complications; therefore, the …

Changes in visual impairment due to diabetic retinopathy during 1980–2019 based on nationwide register data

PKM Purola, MUI Ojamo, M Gissler… - Diabetes Care, 2022 - Am Diabetes Assoc
OBJECTIVE To evaluate changes in the incidence, prevalence, severity, and onset age of
visual impairment (VI) due to diabetic retinopathy (DR) and compare these trends in the …

LRG1 as a novel therapeutic target in eye disease

G De Rossi, ME Da Vitoria Lobo, J Greenwood… - Eye, 2022 - nature.com
Retinal and choroidal diseases are major causes of blindness and visual impairment in the
developed world and on the rise due to an ageing population and diabetes epidemic …

Building on the success of anti-vascular endothelial growth factor therapy: a vision for the next decade

AP Adamis, CJ Brittain, A Dandekar, JJ Hopkins - Eye, 2020 - nature.com
This article aims to identify key opportunities for improvement in the diagnosis and treatment
of retinal disease, and describe recent innovations that will potentially facilitate improved …

The contribution of the English NHS Diabetic Eye Screening Programme to reductions in diabetes-related blindness, comparisons within Europe, and future …

PH Scanlon - Acta diabetologica, 2021 - Springer
The aim of the English NHS Diabetic Eye Screening Programme (DESP) is to reduce the risk
of sight loss amongst people with diabetes by the prompt identification and effective …

An evaluation system of fundus photograph-based intelligent diagnostic technology for diabetic retinopathy and applicability for research

WH Yang, B Zheng, MN Wu, SJ Zhu, FQ Fei, M Weng… - Diabetes Therapy, 2019 - Springer
Abstract Introduction In April 2018, the US Food and Drug Administration (FDA) approved
the world's first artificial intelligence (AI) medical device for detecting diabetic retinopathy …

Retrospective analysis of newly recorded certifications of visual impairment due to diabetic retinopathy in Wales during 2007–2015

RL Thomas, SD Luzio, RV North, S Banerjee… - BMJ open, 2017 - bmjopen.bmj.com
Objective The aim of this study was to analyse the changes in new certifications for both
sight impairment (SI) and severe sight impairment (SSI, blindness) in Wales due to diabetic …

Metabolic memory in mitochondrial oxidative damage triggers diabetic retinopathy

Z Wang, H Zhao, W Guan, X Kang, X Tai, Y Shen - BMC ophthalmology, 2018 - Springer
Background Diabetic retinopathy (DR) is a microvascular complication induced by high
blood glucose. This study was conducted to investigate the effect of metabolic memory on …

The P2X7 receptor: A promising pharmacological target in diabetic retinopathy

M Tassetto, A Scialdone, A Solini… - International journal of …, 2021 - mdpi.com
Diabetes is a worldwide emergency. Its chronic complications impose a heavy burden on
patients, health systems, and on society as a whole. Diabetic retinopathy is one of the most …