The intestine is a vital organ responsible for nutrient absorption, bile and waste excretion,
and a major site of host immunity. In order to keep up with daily demands, the intestine has …

Oxidative enzymes treat weak flours in order to restore the gluten network of damaged
wheat flour and reduce the economic and technological losses. The present review …

The establishment of the anteroposterior (AP) axis is a crucial step during animal embryo
development. In mammals, genetic studies have shown that this process relies on signals …

The discovery of the first heart field (FHF) and the second heart field (SHF) led us to
understand how cardiac lineages and structures arise during development. However, it …

Osteosarcoma (OS) is the most frequent primary malignant bone tumor in urgent need of
better therapies. Using genetically modified mouse models (GEMMs), we demonstrate that …

Differentiation of cardiomyocytes (CMs) from human induced pluripotent stem cells (hiPSCs)
is critically dependent upon the regulation of the Wnt signaling pathway. The mechanisms …

Gene regulatory networks controlling functional activities of spatially and temporally distinct
endodermal cell populations in the early mouse embryo remain ill defined. The T-box …

A striking property of vertebrate embryos is the emergence of a conserved body plan across
a wide range of organisms through the process of gastrulation. As the body plan unfolds …

During embryo development, DNA methylation is established by DNMT3A/3B and
subsequently maintained by DNMT1. While much research has been done in this field, the …

Human-induced pluripotent stem cells (hiPSCs) provide a personalized approach to study
conditions and diseases including those of the eye that lack appropriate animal models to …