Circulating blood is filtered across the glomerular barrier to form an ultrafiltrate of plasma in
the Bowman's space. The volume of glomerular filtration adjusted by time is defined as the …

Congenital anomalies of the kidneys and urinary tracts (CAKUT) are disorders caused by
defects in the development of the kidneys and their outflow tracts. The formation of the …

The overall diagnostic yield of massively parallel sequencing–based tests in patients with
chronic kidney disease (CKD) is 30% for paediatric cases and 6–30% for adult cases. These …

Congenital anomalies of the kidney and urinary tract (CAKUT) are a major cause of pediatric
kidney failure. We performed a genome-wide analysis of copy number variants (CNVs) in …

Congenital anomalies of the kidney and urinary tract (CAKUT) are the most frequent form of
malformation at birth and represent the cause of 40–50% of pediatric and 7% of adult end …

We examined the burden of large, rare, copy-number variants (CNVs) in 192 individuals with
renal hypodysplasia (RHD) and replicated findings in 330 RHD cases from two independent …

Background Unilateral renal agenesis (URA) is associated with other congenital anomalies
of the kidney and urinary tract (CAKUT) and extra-renal anomalies. However, the reported …

Results Of 212,930 patients commencing RRT from 1990 to 2009, 4765 (2.2%) had renal
diagnoses consistent with CAKUT. The proportion of incident RRT patients with CAKUT …

Background. Children with a solitary functioning kidney (SFK) have an increased risk of
developing hypertension, albuminuria and chronic kidney disease in later life. This renal …

MicroRNAs (miRNAs) belong to a class of endogenous small noncoding RNAs that regulate
gene expression at the posttranscriptional level, through both translational repression and …