[HTML][HTML] Stem cell factor inhibition reduces Th2 inflammation and cellular infiltration in a mouse model of eosinophilic esophagitis

C Ptaschinski, D Zhu, W Fonseca, NW Lukacs - Mucosal immunology, 2023 - Elsevier
Eosinophilic esophagitis (EoE) is a T helper (Th) 2-mediated inflammatory disorder
characterized endoscopically by eosinophilic infiltration leading to fibrosis of the esophagus …

[HTML][HTML] Pulmonary immune profiling reveals common inflammatory endotypes of childhood wheeze and suppurative lung disease

MR Neeland, L Gubbels, ATC Wong, H Walker… - Mucosal …, 2024 - Elsevier
Suppurative lung disease and wheezing are common respiratory diseases of childhood,
however, due to poor understanding of underlying pathobiology, there are limited treatment …

[HTML][HTML] Asymptomatic survivors of childhood acute lymphoblastic leukemia demonstrate a biological profile of inflamm-aging early in life

E Latoch, K Konończuk, K Konstantynowicz-Nowicka… - Cancers, 2022 - mdpi.com
Simple Summary The most common malignancy diagnosed in childhood is acute
lymphoblastic leukemia (ALL). With significant advances in ALL treatment and excellent …

Prognostic and clinic-pathological significances of SCF and COX-2 expression in inflammatory and malignant prostatic lesions

MA Alabiad, OA Harb, HF Taha, BS El Shafaay… - Pathology & Oncology …, 2019 - Springer
The initiation of prostatic malignancy has been linked to chronic inflammation. Stem cell
factor (SCF) is an inflammatory cytokine that is specific to the c-KIT receptor which is type III …

[HTML][HTML] Drug-induced mast cell eradication: A novel approach to treat mast cell activation disorders?

P Valent, C Akin, K Hartmann, A Reiter, J Gotlib… - Journal of Allergy and …, 2022 - Elsevier
Mast cell activation is a key event in allergic reactions, other inflammatory states, and mast
cell activation syndromes. Mast cell-stabilizing agents, mediator-targeting drugs and drugs …

[HTML][HTML] Sputum production and salivary microbiome in COVID-19 patients reveals oral-lung axis

KYF Lu, H Alqaderi, S Bin Hasan, H Alhazmi… - PLOS …, 2024 - journals.plos.org
SARS-CoV-2, a severe respiratory disease primarily targeting the lungs, was the leading
cause of death worldwide during the pandemic. Understanding the interplay between the …

Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand KITLG/SCF and Gene-By-Air-Pollution …

ACY Mak, S Sajuthi, J Joo, S Xiao, PM Sleiman… - Genetics, 2020 - academic.oup.com
Baseline lung function is a standard diagnostic criterion used by clinicians to detect lung
diseases. It is a complex trait significantly influenced by both genetics and environmental …

The association of stem cell factor and soluble c-Kit (s-cKit) receptor serum concentrations with the severity and risk prediction of autism spectrum disorders

F Mashayekhi, S Shabani, ST Sasani, Z Salehi - Metabolic Brain Disease, 2022 - Springer
S tem cell factor (SCF) and its receptor (c-kit) signaling play important role in normal brain
physiology including neurogenesis, synapse formation and spatial learning function of the …

[PDF][PDF] 布地奈德联合槐杞黄颗粒治疗小儿哮喘的疗效及对血清LTD4, NGF, TIMP-1 水平的影响

冯爱民, 李晓娟, 杨会侠, 何平, 谢秀春 - 现代生物医学进展, 2017 - biomed.cnjournals.com
摘要目的: 研究布地奈德联合槐杞黄颗粒治疗小儿哮喘的临床疗效及对患儿血清白细胞三烯D4
(LTD4), 神经生长因子(NGF), 基质金属蛋白酶抑制剂-1 (TIMP-1) 水平的影响. 方法: 选取2014 …

Serum level of stem cell factor and its soluble receptor in aspirin-exacerbated respiratory disease

RN Kalmarzi, A Foroutan, M Abdi, P Ataee, A Jalili… - …, 2019 - Taylor & Francis
Aim: Stem cell factor (SCF) may be associated with inflammatory processes leading to
aspirin-induced asthma. This study evaluated the relationship between serum level of SCF …