Mucus is a selective barrier to particles and molecules, preventing penetration to the
epithelial surface of mucosal tissues. Significant advances in transmucosal drug delivery …

Highlights•Mucus filters particles based on size and surface chemistry.•Simple descriptors
like net charge are inadequate predictors for mucus interaction.•A variety of nanoparticle …

At mucosal surfaces throughout the body mucus and mucins regulate interactions between
epithelia and both commensal and pathogenic bacteria. Although the microbes in the female …

Among the components of a healthy life, sexuality is essential, contributing to both the
psychophysical and social well-being of women and, consequently, to their quality of life. A …

Through pregnancy the cervix must simultaneously remain competent for pregnancy
maintenance and yet become progressively compliant to ensure on time parturition. Cervical …

Approaches for effective and sustained drug delivery to the female reproductive tract (FRT)
for treating a range of gynaecological conditions remain limited. The development of …

Cryopreserved ram spermatozoa are limited in their capacity to traverse the ovine cervix and
achieve fertilization. This altered interaction may be related to modified molecular …

The chemical composition of the cervical mucus (CM), its physical characteristics and the
volume of secretion change cyclically throughout the menstrual cycle. The aim of this study …

In species where semen is deposited in the vagina, the cervix has the unique function of
facilitating progress of spermatozoa towards the site of fertilisation while also preventing the …

Hormone-based contraception disrupts hormonal balance, creating artificial states of
anovulation and threatening women's health. We reviewed its main adverse effects and …