Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Fumagillin is a mycotoxin produced, above all, by the saprophytic filamentous fungus
Aspergillus fumigatus. This mold is an opportunistic pathogen that can cause invasive …

The secondary metabolites of fungi are often produced at very low concentrations, and until
recently the regulatory mechanisms of secondary metabolite biosynthesis have been …

Background Recently, a gene cluster responsible for biosynthesis of ustiloxin in Aspergillus
flavus was identified as the first case of a ribosomally synthesized and post-translationally …

Gene clusters are genomic loci that contain multiple genes that are functionally and
genetically linked. Gene clusters collectively encode diverse functions, including small …

Genome-wide comparisons have shown Talaromyces marneffei possessed a stable mating
type locus in its meiosis genes. But the function of the mating type locus in T. marneffei is not …

Fungal secondary metabolites (SMs) have captured the interest of natural products
researchers in academia and industry for decades. In recent years, the high rediscovery rate …

Mating-type transcription factors are master regulators of sexually related signal transduction
pathways in fungi; however, their recognition of specific DNA sequences from target genes …

The origins and maintenance of the rich fungal diversity have been longstanding issues in
evolutionary biology. To investigate how differences in expression regulation contribute to …

Asexuality was considered to be a common feature of a large part of fungi, including those of
the genus Aspergillus. However, recent advances and the available genomic and genetic …