Simple Summary The epithelial to mesenchymal transition (EMT) is a well-documented
process in the study of cancer metastases. The cytoskeleton is an intricate network involved …

This article is part of a Minifocus on microtubule dynamics. For further reading, please see
related articles:'Kinesins at a glance'by Sharyn A. Endow et al.,(J. Cell Sci. 123, pp. 3420 …

During spermatogenesis, developing germ cells are transported across the seminiferous
epithelium. Studies propose that because microtubules (MTs) serve as the tracks for …

The proliferation and steroid hormone synthesis of granulosa cells (GCs) are essential for
ovarian follicle growth and ovulation, which are necessary to support the normal function of …

Although termed central body, the centrosome is located off-center in many polarized cells. T
cell receptor (TCR) engagement by antigens induces a polarity switch in T cells. This leads …

The eyespot of the unicellular green alga Chlamydomonas reinhardtii is a photoreceptive
organelle required for phototaxis. Relative to the anterior flagella, the eyespot is …

The microtubule (MT) system is important for many aspects of neuronal function, including
motility, differentiation, and cargo trafficking. Parkinson's disease (PD) is associated with …

Natural microtubules typically include one A-lattice seam within an otherwise helically
symmetric B-lattice tube. It is currently unclear how A-lattice seams influence microtubule …

Background and Purpose Drugs targeting microtubules are commonly used for cancer
treatment. However, the potency of microtubule inhibitors used clinically is limited by the …

Toxoplasma gondii is the causative agent of toxoplasmosis. The pathogenicity of this
unicellular parasite is tightly linked to its ability to efficiently proliferate within its host …