Consensus on diagnosis and management of Cushing's disease: a guideline update

M Fleseriu, R Auchus, I Bancos… - The lancet Diabetes & …, 2021 - thelancet.com
Cushing's disease requires accurate diagnosis, careful treatment selection, and long-term
management to optimise patient outcomes. The Pituitary Society convened a consensus …

Diagnosis and management of pituitary adenomas: a review

NA Tritos, KK Miller - Jama, 2023 - jamanetwork.com
Importance Pituitary adenomas are neoplasms of the pituitary adenohypophyseal cell
lineage and include functioning tumors, characterized by the secretion of pituitary hormones …

Pituitary-tumor endocrinopathies

S Melmed - New England Journal of Medicine, 2020 - Mass Medical Soc
Pituitary-Tumor Endocrinopathies Pituitary adenomas account for about 15% of intracranial
tumors. Clinical manifestations of disease reflect the oversecretion of the involved hormone …

Diagnosis and treatment of pituitary adenomas: a review

ME Molitch - Jama, 2017 - jamanetwork.com
Importance Pituitary adenomas may hypersecrete hormones or cause mass effects.
Therefore, early diagnosis and treatment are important. Observations Prevalence of pituitary …

Treatment of Cushing's syndrome: an endocrine society clinical practice guideline

LK Nieman, BMK Biller, JW Findling… - The Journal of …, 2015 - academic.oup.com
Objective: The objective is to formulate clinical practice guidelines for treating Cushing's
syndrome. Participants: Participants include an Endocrine Society-appointed Task Force of …

Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity

H Yang, L Xia, J Chen, S Zhang, V Martin, Q Li, S Lin… - Nature medicine, 2019 - nature.com
Psychological distress has long been suspected to influence cancer incidence and mortality.
It remains largely unknown whether and how stress affects the efficacy of anticancer …

Efficacy and safety of osilodrostat in patients with Cushing's disease (LINC 3): a multicentre phase III study with a double-blind, randomised withdrawal phase

R Pivonello, M Fleseriu, J Newell-Price… - The Lancet Diabetes & …, 2020 - thelancet.com
Background Cushing's disease is a rare endocrine disorder characterised by cortisol
overproduction with severe complications. Therapies for cortisol reduction are often …

Complications of Cushing's syndrome: state of the art

R Pivonello, AM Isidori, MC De Martino… - The lancet Diabetes & …, 2016 - thelancet.com
Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and
excessive secretion of cortisol. The syndrome is associated with increased mortality and …

Adrenocortical carcinoma

T Else, AC Kim, A Sabolch, VM Raymond… - Endocrine …, 2014 - academic.oup.com
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy, often with an unfavorable
prognosis. Here we summarize the knowledge about diagnosis, epidemiology …

[HTML][HTML] Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade

VK Arora, E Schenkein, R Murali, SK Subudhi… - Cell, 2013 - cell.com
The treatment of advanced prostate cancer has been transformed by novel antiandrogen
therapies such as enzalutamide. Here, we identify induction of glucocorticoid receptor (GR) …