The striatum is essential for learning which actions lead to reward and for implementing
those actions. Decades of experimental and theoretical work have led to several influential …

The striatal and pallidal complexes are basal ganglia structures that orchestrate learning
and execution of flexible behavior. Models of how the basal ganglia subserve these …

The basal ganglia are known to influence action selection and modulation of movement
vigor, but whether and how they contribute to specifying the kinematics of learned motor …

The cortex projects to the dorsal striatum topographically, to regulate behaviour,–, but
spiking activity in the two structures has previously been reported to have markedly different …

Beat perception offers cognitive scientists an exciting opportunity to explore how cognition
and action are intertwined in the brain even in the absence of movement. Many believe the …

The neural mechanisms that generate an extensible library of motor motifs and flexibly string
them into arbitrary sequences are unclear. We developed a model in which inhibitory basal …

A classic view of the striatum holds that activity in direct and indirect pathways oppositely
modulates motor output. Whether this involves direct control of movement, or reflects a …

The ability to suppress actions that lead to a negative outcome and explore alternative
actions is necessary for optimal decision making. Although the basal ganglia have been …

The role of the striatum in motor control is commonly assumed to be mediated by the two
striatal efferent pathways characterized by striatal projection neurons (SPNs) expressing …

The synaptic pathways in the striatum are central to basal ganglia functions including motor
control, learning and organization, action selection, acquisition of motor skills, cognitive …