Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia‐reperfusion injury and preconditioning

P Ferdinandy, R Schulz - British journal of pharmacology, 2003 - Wiley Online Library
There appears to be a controversy in the study of myocardial ischaemia‐reperfusion injury
and preconditioning whether nitric oxide (NO) plays a protective or detrimental role. A …

Sarcolemmal Versus Mitochondrial ATP-Sensitive K+ Channels and Myocardial Preconditioning

GJ Gross, RM Fryer - Circulation research, 1999 - Am Heart Assoc
Ischemic preconditioning (IPC) is a phenomenon in which single or multiple brief periods of
ischemia have been shown to protect the heart against a more prolonged ischemic insult …

Anaesthetics and cardiac preconditioning. Part I. Signalling and cytoprotective mechanisms

M Zaugg, E Lucchinetti, M Uecker… - British journal of …, 2003 - academic.oup.com
Cardiac preconditioning represents the most potent and consistently reproducible method of
rescuing heart tissue from undergoing irreversible ischaemic damage. Major milestones …

Rabbit heart can be “preconditioned” via transfer of coronary effluent

EW Dickson, M Lorbar, WA Porcaro… - American Journal …, 1999 - journals.physiology.org
Brief myocardial ischemia not only evokes a local cardioprotective or “preconditioning” effect
but also can render remote myocardium resistant to sustained ischemia. We propose the …

Myocardial apoptosis and ischemic preconditioning

ZQ Zhao, J Vinten-Johansen - Cardiovascular research, 2002 - academic.oup.com
Necrosis and apoptosis are two forms of cell death in the myocardium that have been
associated with ischemia and reperfusion. Although it has been well documented that …

[HTML][HTML] Retinal preconditioning and the induction of heat-shock protein 27

Y Li, S Roth, M Laser, J Ma… - … ophthalmology & visual …, 2003 - arvojournals.org
purpose. Brief periods of ischemia have been shown to protect the retina from potentially
damaging periods of ischemia. This phenomenon has been termed ischemic …

Remote ischemic preconditioning: current knowledge, unresolved questions, and future priorities

K Przyklenk, P Whittaker - Journal of cardiovascular …, 2011 - journals.sagepub.com
Remote ischemic preconditioning (RIPC) is the phenomenon whereby brief episodes of
ischemia–reperfusion applied in distant tissues or organs render the myocardium resistant …

Preconditioning, postconditioning and their application to clinical cardiology

RA Kloner, SH Rezkalla - Cardiovascular Research, 2006 - academic.oup.com
Ischemic preconditioning is a well-established phenomenon first described in experimental
preparations in which brief episodes of ischemia/reperfusion applied prior to a longer …

Protecting the ischaemic and reperfused myocardium in acute myocardial infarction: distant dream or near reality?

DM Yellon, GF Baxter - Heart, 2000 - heart.bmj.com
Acute coronary occlusion is the leading cause of morbidity and mortality in the Western
world, and according to the World Health Organisation will be the major cause of death in …

Ischemic preconditioning suppresses ventricular tachyarrhythmias after myocardial revascularization

ZK Wu, T Iivainen, E Pehkonen, J Laurikka… - Circulation, 2002 - Am Heart Assoc
Background—Ventricular fibrillation (VF) and tachycardia (VT) are the common and potential
life-threatening complications after CABG. Ischemic preconditioning (IP) has been proved …