Innate and adaptive immune memory: an evolutionary continuum in the host's response to pathogens

MG Netea, A Schlitzer, K Placek, LAB Joosten… - Cell host & …, 2019 - cell.com
Immunological memory is an important evolutionary trait that improves host survival upon
reinfection. Memory is a characteristic recognized within both the innate and adaptive arms …

Human immunology and immunotherapy: main achievements and challenges

J Varadé, S Magadán… - Cellular & Molecular …, 2021 - nature.com
The immune system is a fascinating world of cells, soluble factors, interacting cells, and
tissues, all of which are interconnected. The highly complex nature of the immune system …

Clonal expansion and epigenetic inheritance of long-lasting NK cell memory

T Rückert, CA Lareau, MF Mashreghi, LS Ludwig… - Nature …, 2022 - nature.com
Clonal expansion of cells with somatically diversified receptors and their long-term
maintenance as memory cells is a hallmark of adaptive immunity. Here, we studied …

[HTML][HTML] Imprinting of the immune system by the microbiota early in life

Z Al Nabhani, G Eberl - Mucosal immunology, 2020 - Elsevier
The ontogeny and maturation of the immune system is modulated by the microbiota. During
fetal life, the mother's microbiota produces compounds that are transferred to the fetus and …

Innate immune memory in invertebrate metazoans: a critical appraisal

D Melillo, R Marino, P Italiani, D Boraschi - Frontiers in Immunology, 2018 - frontiersin.org
The ability of developing immunological memory, a characteristic feature of adaptive
immunity, is clearly present also in innate immune responses. In fact, it is well known that …

Shift in Immune Parameters After Repeated Exposure to Nanoplastics in the Marine Bivalve Mytilus

M Auguste, T Balbi, C Ciacci, B Canonico… - Frontiers in …, 2020 - frontiersin.org
Bivalves are widespread in coastal environments subjected to a wide range of
environmental fluctuations: however, the rapidly occurring changes due to several …

Innate immune memory in invertebrates: Concept and potential mechanisms

H Lanz-Mendoza, J Contreras-Garduño - Developmental & Comparative …, 2022 - Elsevier
Invertebrates are the protagonists of a recent paradigm shift because they now show that
vertebrates are not the only group with immune memory. This review discusses the concept …

Remodeled tumor immune microenvironment (TIME) parade via natural killer cells reprogramming in breast cancer

MM Elanany, DM Mostafa, NM Hamdy - Life Sciences, 2023 - Elsevier
Breast cancer (BC) is the main cause of cancer-related mortality among women globally.
Despite substantial advances in the identification and management of primary tumors …

[图书][B] Philosophy of immunology

T Pradeu - 2020 - cambridge.org
Immunology is central to contemporary biology and medicine, but it also provides novel
philosophical insights. Its most significant contribution to philosophy concerns the …

Themis2 regulates natural killer cell memory function and formation

T Nabekura, EA Deborah, S Tahara, Y Arai… - Nature …, 2023 - nature.com
Immunological memory is a hallmark of the adaptive immune system. Although natural killer
(NK) cells are innate immune cells important for the immediate host defence, they can …