[HTML][HTML] Brain extended and closed forms glutathione levels decrease with age and extended glutathione is associated with visuospatial memory
X Hu, K Pan, M Zhao, J Lv, J Wang, X Zhang, Y Liu… - NeuroImage, 2024 - Elsevier
During aging, the brain is subject to greater oxidative stress (OS), which is thought to play a
critical role in cognitive impairment. Glutathione (GSH), as a major antioxidant in the brain …
critical role in cognitive impairment. Glutathione (GSH), as a major antioxidant in the brain …
[HTML][HTML] Early-life exposure to traffic-related air pollutants induced anxiety-like behaviors in rats via neurotransmitters and neurotrophic factors
C Kyi-Tha-Thu, Y Fujitani, S Hirano… - International Journal of …, 2022 - mdpi.com
Recent epidemiological studies have reported significantly increasing hospital admission
rates for mental disorders such as anxiety and depression, not only in adults but also in …
rates for mental disorders such as anxiety and depression, not only in adults but also in …
[HTML][HTML] Examining the role of paraoxonase 2 in the dopaminergic system of the mouse brain
JM Garrick, K Dao, LG Costa, J Marsillach… - BMC neuroscience, 2022 - Springer
Abstract Background Paraoxonase 2 (PON2) is an intracellular antioxidant enzyme located
at the inner mitochondrial membrane. Previous studies have found PON2 to be an important …
at the inner mitochondrial membrane. Previous studies have found PON2 to be an important …
[HTML][HTML] Age-associated sex difference in the expression of mitochondria-based redox sensitive proteins and effect of pioglitazone in nonhuman primate brain
S Jamwal, JK Blackburn, JD Elsworth - Biology of sex Differences, 2023 - Springer
Abstract Background Paraoxonase 2 (PON2) and neuronal uncoupling proteins (UCP4 and
UCP5) possess antioxidant, anti-apoptotic activities and minimize accumulation of reactive …
UCP5) possess antioxidant, anti-apoptotic activities and minimize accumulation of reactive …
Expression of PON2 isoforms varies among brain regions in male and female African green monkeys
S Jamwal, JK Blackburn, JD Elsworth - Free Radical Biology and Medicine, 2022 - Elsevier
Mitochondrial dysfunction and oxidative stress contribute to the neuropathology of
neurodegenerative disorders such as Parkinson's disease (PD). Paraoxonase-2 (PON2) is a …
neurodegenerative disorders such as Parkinson's disease (PD). Paraoxonase-2 (PON2) is a …
Reduced brain glutathione levels during normal aging are associated with visuospatial memory
X Hu, K Pan, M Zhao, J Lv, J Wang, X Zhang, Y Liu… - bioRxiv, 2023 - biorxiv.org
During aging, the brain is subject to greater oxidative stress (OS), which is thought to play a
critical role in cognitive impairment. Glutathione (GSH), as a major antioxidant in the brain …
critical role in cognitive impairment. Glutathione (GSH), as a major antioxidant in the brain …