Liposomes are well recognised as effective drug delivery systems, with a range of products
approved, including follow on generic products. Current manufacturing processes used to …

Cells are integral to all forms of life due to their compartmentalization by the plasma
membrane. However, living organisms are immensely complex. Thus there is a need for …

The nuclear envelope (NE) is a spherical double membrane with elastic properties. How NE
shape and elasticity are regulated by lipid chemistry is unknown. Here we discover lipid acyl …

Recent years have seen substantial efforts aimed at constructing artificial cells from various
molecular components with the aim of mimicking the processes, behaviours and …

Liposomes (or lipid vesicles) are a versatile platform as carriers for the delivery of the drugs
and other macromolecules into human and animal bodies. Though the method of using …

Against a backdrop of global antibiotic resistance and increasing awareness of the
importance of the human microbiota, there has been resurgent interest in the potential use of …

Compartments for the spatially and temporally controlled assembly of biological processes
are essential towards cellular life. Synthetic mimics of cellular compartments based on lipid …

Endomembrane damage represents a form of stress that is detrimental for eukaryotic cells,.
To cope with this threat, cells possess mechanisms that repair the damage and restore …

With the ultimate aim to construct a living cell, bottom-up synthetic biology strives to
reconstitute cellular phenomena in vitro–disentangled from the complex environment of a …

The proliferation of life on earth is based on the ability of single cells to divide into two
daughter cells. During cell division, the plasma membrane undergoes a series of …