The macrophage in HIV-1 infection: from activation to deactivation?

G Herbein, A Varin - Retrovirology, 2010 - Springer
Macrophages play a crucial role in innate and adaptative immunity in response to
microorganisms and are an important cellular target during HIV-1 infection. Recently, the …

Macrophage signaling in HIV-1 infection

G Herbein, G Gras, KA Khan, W Abbas - Retrovirology, 2010 - Springer
The human immunodeficiency virus-1 (HIV-1) is a member of the lentivirus genus. The virus
does not rely exclusively on the host cell machinery, but also on viral proteins that act as …

HIV and inflammation

AZ Decrion, I Dichamp, A Varin… - Current HIV research, 2005 - ingentaconnect.com
A main feature of HIV infection is the expression of several proinflammatory cytokines.
Proinflammatory cytokines expressed as soluble factors or membrane-bound molecules …

Human immunodeficiency virus type-1 and chemokines: beyond competition for common cellular receptors

TS Stantchev, CC Broder - Cytokine & growth factor reviews, 2001 - Elsevier
The chemokines and their receptors have been receiving exceptional attention in recent
years following the discoveries that some chemokines could specifically block human …

CCR5 susceptibility to ligand-mediated down-modulation differs between human T lymphocytes and myeloid cells

JM Fox, R Kasprowicz, O Hartley… - Journal of Leucocyte …, 2015 - academic.oup.com
CCR5 is a chemokine receptor expressed on leukocytes and a coreceptor used by HIV-1 to
enter CD4+ T lymphocytes and macrophages. Stimulation of CCR5 by chemokines triggers …

Macrophage activation and HIV infection: can the Trojan horse turn into a fortress?

G Herbein, A Coaquette… - Current molecular …, 2002 - ingentaconnect.com
Macrophages are infected early during HIV infection and are thought to play the role of a
Trojan horse by spreading infection in tissues. Most recent studies point out to a more …

Opposite effects of IL-10 on the ability of dendritic cells and macrophages to replicate primary CXCR4-dependent HIV-1 strains

P Ancuta, Y Bakri, N Chomont, H Hocini… - The Journal of …, 2001 - journals.aai.org
We investigated the effect of IL-10 on replication of primary CXCR4-dependent (X4) HIV-1
strains by monocyte-derived dendritic cells (DCs) and macrophages (MΦs). MΦs efficiently …

Macrophage-Derived Factors with the Potential to Contribute to Pathogenicity of HIV-1 and HIV-2: Role of CCL-2/MCP-1

C Gao, W Ouyang, J Kutza, TA Grimm, K Fields… - Viruses, 2023 - mdpi.com
Human immunodeficiency virus type 2 (HIV-2) is known to be less pathogenic than HIV-1.
However, the mechanism (s) underlying the decreased HIV-2 pathogenicity is not fully …

Synthesis and characterization of biologically functional biotinylated RANTES

C Vita, E Drakopoulou, L Ylisastigui, Y Bakri… - Journal of …, 2002 - Elsevier
Development of specifically labeled chemokines that retain their biological properties should
be useful for analyzing their mechanisms of action both under physiological and …

Consistent and Significant Inhibition of Human Immunodeficiency Virus Type 1 Envelope-Mediated Membrane Fusion by μ-Chemokines (RANTES) in Primary Human …

TS Stantchev, CC Broder - The Journal of infectious diseases, 2000 - academic.oup.com
Infection and entry of CD4+ cells by human immunodeficiency virus type 1 (HIV-1) requires a
coreceptor molecule, which, in concert with CD4, interacts with the viral envelope …