The midcycle surge of LH sets in motion interconnected networks of signaling cascades to
bring about rupture of the follicle and release of the oocyte during ovulation. Many mediators …

This review provides a detailed description of matrix metalloproteinases (MMPs), focusing
on those that are known to have critical roles in bone and periodontal disease. Periodontal …

Matrix metalloproteases (MMPs) comprise a family of enzymes that cleave protein substrates
based on a conserved mechanism involving activation of an active site-bound water …

Matrix metalloproteinases (MMPs), also designated matrixins, hydrolyze components of the
extracellular matrix. These proteinases play a central role in many biological processes …

Matrix metalloproteinases (MMPs), also designated matnxms, are a family of related zinc
metalloendopeptidases that function in the turnover of components of the extracellular …

▪ Abstract The matrix metalloproteinases (MMPs) constitute a multigene family of over 25
secreted and cell surface enzymes that process or degrade numerous pericellular …

Ischemic stroke continues to be one of the most challenging diseases in translational
neurology. Tissue plasminogen activator (tPA) remains the only approved treatment for …

Introduction 3. Cartilage in health and disease 4. Connective tissue degradation in arthritis
5. MMPs and cartilage degradation 6. Regulation of MMP gene expression in arthritis 7 …

Idiopathic pulmonary fibrosis is a progressive and usually fatal lung disease characterized
by fibroblast proliferation and extracellular matrix remodeling, which result in irreversible …

The matrix metalloproteinases (MMPs) play a key role in the normal physiology of
connective tissue during development, morphogenesis and wound healing, but their …