Intermolecular addition of carbon-centered radicals to ynamides. a regio-and stereoselective route to persubstituted α-iodo-enamides
Rather surprisingly, C–C bond formation through “intermolecular” radical addition to internal
ynamides has never been reported. Actually, ynamides are excellent acceptors for …
ynamides has never been reported. Actually, ynamides are excellent acceptors for …
Insights into the cobalt-catalyzed three-component coupling of mixed aromatic organozinc species, carbonyl compounds or imines and Michael acceptors: Synthetic …
J Paul, M Presset, E Le Gall, E Leonel, P Retailleau - Synthesis, 2018 - thieme-connect.com
The first examples of cobalt-catalyzed multicomponent couplings of mixed aromatic arylzinc
reagents with Michael acceptors and carbonyl compounds or imines is described. The …
reagents with Michael acceptors and carbonyl compounds or imines is described. The …
Striking Difference between Succinimidomethyl and Phthalimidomethyl Radicals in Conjugate Addition to Alkylidenemalonate Initiated by Dimethylzinc
K Yamada, Y Matsumoto, S Fujii, T Konishi… - The Journal of …, 2016 - ACS Publications
We used dimethylzinc to develop a conjugate addition reaction of imidomethyl radicals to
alkylidenemalonates, in which we observed a significant difference between …
alkylidenemalonates, in which we observed a significant difference between …
The rationale for stereoinduction in conjugate addition to alkylidenemalonates bearing a menthol-derived chiral auxiliary
K Yamada, S Fujiwara, T Inokuma, M Sugano… - Tetrahedron, 2021 - Elsevier
Density-functional theory (DFT) calculations provided a new model to rationalize the
stereoselectivity in the asymmetric addition to alkylidenemalonate bearing 8-phenylmenthyl …
stereoselectivity in the asymmetric addition to alkylidenemalonate bearing 8-phenylmenthyl …
Asymmetric Tandem Conjugate Addition–Aldol Condensation with N‐Acryloyloxazolidines Derived from 2‐Phenylglycinol
I Zelocualtecatl‐Montiel… - Asian Journal of …, 2017 - Wiley Online Library
Abstract The tandem 1, 4‐addition–aldol condensation reaction of diethylzinc, α, β‐
unsaturated chiral enantiopure oxazolidines derived from 2‐phenylglycinol, and carbonyl …
unsaturated chiral enantiopure oxazolidines derived from 2‐phenylglycinol, and carbonyl …
[HTML][HTML] α-(Aminomethyl) acrylates as acceptors in radical–polar crossover 1, 4-additions of dialkylzincs: insights into enolate formation and trapping
A Palillero-Cisneros… - Beilstein Journal of …, 2023 - beilstein-journals.org
We demonstrate that α-(aminomethyl) acrylates are suitable acceptors for 1, 4-additions of
dialkylzincs in aerobic conditions. The air-promoted radical–polar crossover process …
dialkylzincs in aerobic conditions. The air-promoted radical–polar crossover process …
Reactivity of benzylidene and alkylidenemalonates in radical addition mediated with dialkylzincs–An intriguing story
Benzylidene-and alkylidenemalonates are extremely reactive radical acceptors in
dialkylzinc-mediated radical additions. Theoretical investigations showed that the multi-step …
dialkylzinc-mediated radical additions. Theoretical investigations showed that the multi-step …