Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …

A large number of hydrophilic and hydrophobic carriers in pharmaceutical excipients are
available today which are used for formulation of solid dispersions. Depending on nature of …

The present study investigates the possibility of using poloxamers as solubility and
dissolution rate enhancing agents of the poorly water soluble drug substance desloratadine …

An oral route of administration is a most acceptable route for a patient, so we designed
chemically cross‐linked polyethylene glycol‐co‐poly (methacrylic acid) oral hydrogels …

Importance of the field: Although the solid dispersion method has been known to increase
the dissolution rate of poorly water-soluble drugs by dispersing them in hydrophilic carriers …

The solubility behavior of drugs remains one of the most challenging aspects in formulation
development. Solid dispersions (SD) and inclusion complexes (IC) are two of the most …

The aim of this study was to enhance the solubility of rosuvastatin (RST) calcium by
developing β-cyclodextrin-g-poly (2-acrylamido-2-methylpropane sulfonic acid [AMPS]) …

Gliclazide is a second-generation hypoglycemic sulfonylurea, which is useful in the
treatment of non-insulin-dependent diabetes mellitus. It has low bioavailability because of its …

Solubility of poorly water‐soluble drugs is one of the most emerging issue associated with
these drugs to form a suitable dosage form that will provide desired pharmacological …

Fibrinolytic proteases are enzymes that provide a promising alternative to drugs for
thrombolytic therapy, since they degrade fibrin, the major component of blood clots …