New insights into acute pancreatitis
PJ Lee, GI Papachristou - Nature reviews Gastroenterology & …, 2019 - nature.com
The incidence of acute pancreatitis continues to increase worldwide, and it is one of the
most common gastrointestinal causes for hospital admission in the USA. In the past decade …
most common gastrointestinal causes for hospital admission in the USA. In the past decade …
Organ failure due to systemic injury in acute pancreatitis
PK Garg, VP Singh - Gastroenterology, 2019 - Elsevier
Acute pancreatitis may be associated with both local and systemic complications. Systemic
injury manifests in the form of organ failure, which is seen in approximately 20% of all cases …
injury manifests in the form of organ failure, which is seen in approximately 20% of all cases …
Olezarsen, acute pancreatitis, and familial chylomicronemia syndrome
ESG Stroes, VJ Alexander… - … England Journal of …, 2024 - Mass Medical Soc
Background Familial chylomicronemia syndrome is a genetic disorder associated with
severe hypertriglyceridemia and severe acute pancreatitis. Olezarsen reduces the plasma …
severe hypertriglyceridemia and severe acute pancreatitis. Olezarsen reduces the plasma …
Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase …
I Gouni-Berthold, VJ Alexander, Q Yang… - The lancet Diabetes & …, 2021 - thelancet.com
Background Volanesorsen is an antisense oligonucleotide that targets hepatic
apolipoprotein C-III synthesis and reduces plasma triglyceride concentration. The aim of this …
apolipoprotein C-III synthesis and reduces plasma triglyceride concentration. The aim of this …
A modern approach to dyslipidemia
AJ Berberich, RA Hegele - Endocrine reviews, 2022 - academic.oup.com
Lipid disorders involving derangements in serum cholesterol, triglycerides, or both are
commonly encountered in clinical practice and often have implications for cardiovascular …
commonly encountered in clinical practice and often have implications for cardiovascular …
Hypertriglyceridemia and acute pancreatitis
AL Yang, J McNabb-Baltar - Pancreatology, 2020 - Elsevier
Hypertriglyceridemia is the third most common cause of acute pancreatitis. It typically occurs
in patients with an underlying disorder of lipoprotein metabolism and in the presence of a …
in patients with an underlying disorder of lipoprotein metabolism and in the presence of a …
Management of hypertriglyceridemia induced acute pancreatitis
R Garg, T Rustagi - BioMed research international, 2018 - Wiley Online Library
Hypertriglyceridemia is an uncommon but a well‐established etiology of acute pancreatitis
leading to significant morbidity and mortality. The risk and severity of acute pancreatitis …
leading to significant morbidity and mortality. The risk and severity of acute pancreatitis …
Acute pancreatitis: a multifaceted set of organelle and cellular interactions
Acute pancreatitis is an inflammatory disorder of the exocrine pancreas associated with
tissue injury and necrosis. The disease can be mild, involving only the pancreas, and …
tissue injury and necrosis. The disease can be mild, involving only the pancreas, and …
Obesity and pancreatitis
B Khatua, B El-Kurdi, VP Singh - Current opinion in …, 2017 - journals.lww.com
We discuss how obesity may contribute to increasing acute pancreatitis incidence, the role
of lipolytic unsaturated fatty acid release in worsening acute pancreatitis, and potential …
of lipolytic unsaturated fatty acid release in worsening acute pancreatitis, and potential …