Faecal incontinence, which is defined by the unintentional loss of solid or liquid stool, has a
worldwide prevalence of≤ 7% in community-dwelling adults and can markedly impair …

The act of defaecation, although a ubiquitous human experience, requires the coordinated
actions of the anorectum and colon, pelvic floor musculature, and the enteric, peripheral and …

Our understanding of human colonic motility, and autonomic reflexes that generate motor
patterns, has increased markedly through high-resolution manometry. Details of the motor …

We report the first study assessing human colon manometric features and their correlations
with changes in autonomic functioning in patients with refractory chronic constipation prior to …

Background High‐resolution colonic manometry gives an unprecedented window into motor
patterns of the human colon. Our objective was to characterize motor activities throughout …

Characterization of high-amplitude propagating pressure waves (HAPWs or HAPCs) plays a
key role in diagnosis of colon dysmotility using any type of colonic manometry. With the …

Effective and widely available strategies are needed to diagnose colonic motility
dysfunction. We investigated whether ultrasonography could generate spatiotemporal maps …

This work used in vivo MRI images of human colon wall motion to inform a biorelevant
Dynamic Colon Model (DCM) to understand the interplay of wall motion, volume, viscosity …

Contraction patterns of the human colon are rarely discussed from the perspective of its
haustra. Colonic motility was analyzed in 21 healthy subjects using 84-sensor manometry …

Patients with irritable bowel syndrome (IBS) have recurrent lower abdominal pain,
associated with altered bowel habit (diarrhea and/or constipation). As bowel habit is altered …