Worldwide emergence of fluconazole-resistant Candida parapsilosis: current framework and future research roadmap

F Daneshnia, JN de Almeida Júnior, M Ilkit… - The Lancet …, 2023 - thelancet.com
Candida parapsilosis is one of the most commen causes of life-threatening candidaemia,
particularly in premature neonates, individuals with cancer of the haematopoietic system …

Advances in biosensing: The CRISPR/Cas system as a new powerful tool for the detection of nucleic acids

A Bonini, N Poma, F Vivaldi, A Kirchhain… - … of pharmaceutical and …, 2021 - Elsevier
A main challenge in the development of biosensing devices for the identification and
quantification of nucleic acids is to avoid the amplification of the genetic material from the …

[HTML][HTML] Impact of Mycobacteroides abscessus colony morphology on biofilm formation and antimicrobial resistance

AM Oschmann-Kadenbach, C Schaudinn… - International Journal of …, 2024 - Elsevier
Mycobacteroides abscessus is one of the most resistant bacteria so far known and causes
severe and hard to treat lung infections in predisposed patients such as those with Cystic …

Applications of CRISPR/Cas gene-editing technology in yeast and fungi

B Liao, X Chen, X Zhou, Y Zhou, Y Shi, X Ye… - Archives of …, 2022 - Springer
Genome editing technology has progressed rapidly in recent years. Although traditional
gene-editing methods, including homologous recombination, zinc finger endonucleases …

CRISPR-Based Genetic Manipulation of Candida Species: Historical Perspectives and Current Approaches

D Uthayakumar, J Sharma, L Wensing… - Frontiers in Genome …, 2021 - frontiersin.org
The Candida genus encompasses a diverse group of ascomycete fungi that have captured
the attention of the scientific community, due to both their role in pathogenesis and emerging …

Bibliometric analysis and thematic review of Candida pathogenesis: Fundamental omics to applications as potential antifungal drugs and vaccines

SJ Lim, ND Muhd Noor, S Sabri… - Medical …, 2024 - academic.oup.com
Invasive candidiasis caused by the pathogenic Candida yeast species has resulted in
elevating global mortality. The pathogenicity of Candida spp. is not only originated from its …

Using Genomics to Shape the Definition of the Agglutinin-Like Sequence (ALS) Family in the Saccharomycetales

SH Oh, K Schliep, A Isenhower… - Frontiers in Cellular …, 2021 - frontiersin.org
The Candida albicans agglutinin-like sequence (ALS) family is studied because of its
contribution to cell adhesion, fungal colonization, and polymicrobial biofilm formation. The …

A Candida parapsilosis Overexpression Collection Reveals Genes Required for Pathogenesis

SE Pál, R Tóth, JD Nosanchuk, C Vágvölgyi, T Németh… - Journal of Fungi, 2021 - mdpi.com
Relative to the vast data regarding the virulence mechanisms of Candida albicans, there is
limited knowledge on the emerging opportunistic human pathogen Candida parapsilosis …

Features of the rare pathogen Meyerozyma guilliermondii strain SO and comprehensive in silico analyses of its adherence-contributing virulence factor agglutinin …

SJ Lim, ND Muhd Noor, S Sabri… - Journal of …, 2023 - Taylor & Francis
Meyerozyma guilliermondii is a rare yeast pathogen contributing to the deadly invasive
candidiasis. M. guilliermondii strain SO, as a promising protein expression host, showed …

Genetic Manipulation as a Tool to Unravel Candida parapsilosis Species Complex Virulence and Drug Resistance: State of the Art

M Zoppo, N Poma, M Di Luca, D Bottai, A Tavanti - Journal of Fungi, 2021 - mdpi.com
An increase in the rate of isolation of Candida parapsilosis in the past decade, as well as
increased identification of azole-resistant strains are concerning, and require better …