The precise temporal and spatial coordination of histone lysine methylation dynamics across
the epigenome regulates virtually all DNA-templated processes. A large number of histone …

Abstract The Genitourinary Pathology Society (GUPS) reviewed recent advances in renal
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …

Introduction In recent years, molecular characterization of renal cell carcinoma has
facilitated the identification of driver genes, specific molecular pathways, and …

Sarcomatoid and rhabdoid (S/R) renal cell carcinoma (RCC) are highly aggressive tumors
with limited molecular and clinical characterization. Emerging evidence suggests immune …

Background It has been suggested that bladder cancer can be divided into two molecular
subtypes referred to as luminal and basal with distinct clinical behaviors and sensitivities to …

Background Progression of conventional urothelial carcinoma of the bladder to a tumor with
unique microscopic features referred to as micropapillary carcinoma is coupled with …

Purpose: Sarcomatoid renal cell carcinoma (SRCC) ranks among the most aggressive
clinicopathologic phenotypes of RCC. However, the paucity of high-quality, genome-wide …

Oral cavity squamous cell carcinoma is the most common type of head and neck carcinoma.
Its incidence is increasing worldwide, and it is associated with major morbidity and mortality …

Undifferentiated (anaplastic) and rhabdoid cell features are increasingly recognized as
adverse prognostic findings in renal cell carcinoma (RCC), but their molecular pathogenesis …

Non-clear cell renal cell carcinomas are a miscellaneous group of tumors that include
different histological subtypes, each one characterized by peculiarity in terms of genetic …