Reductive amination plays a paramount role in pharmaceutical and medicinal chemistry
owing to its synthetic merits and the ubiquitous presence of amines among biologically …

Conspectus Developing new methods that enable the synthesis of new and complex
molecules with complete control of their 3-D shape is central to the advancement of synthetic …

The formation of highly enantioenriched boronic esters through both stoichiometric and
catalytic methods has received much attention over the past decade. Accordingly, the …

Presented is the first enantioselective copper‐catalyzed 1, 6‐conjugate addition of bis
(pinacolato) diboron to para‐quinone methides. The reaction proceeds with excellent yields …

Catalytic enantiotopic-group-selective cross-couplings of achiral geminal bis
(pinacolboronates) provide a route for the construction of nonracemic chiral …

In planning organic syntheses, disconnections are most often made adjacent to functional
groups, which assist in C–C bond formation. For molecules devoid of obvious functional …

There has recently been an increased interest in active pharmaceutical agents and various
other molecules that contain the 1, 1‐diaryl stereocenter. This has led to the development of …

The Matteson reaction is the nucleophilic displacement of a leaving group from the α‐carbon
of an alkylboronic ester. The reaction proceeds through an (α‐haloalkyl) boronate complex …

A highly efficient enantioselective [1, 3] O-to-C rearrangement of racemic vinyl ethers that
operates under mild conditions was developed. This method with chiral ferrous complex …

The ability to assemble organic molecules one carbon atom at a time has been a long-held
dream for chemists. Modern boronate homologations with chiral carbenoids allow for the …