Coronary artery disease is the leading global cause of mortality. Long recognized to be
heritable, recent advances have started to unravel the genetic architecture of the disease …

Despite the success of LDL-lowering drugs in reducing cardiovascular disease (CVD), there
remains a large burden of residual disease due in part to persistent dyslipidemia …

BACKGROUND Metabolism can be broadly divided into anabolic, energy-consuming,
biosynthetic processes and energy-generating catabolic processes. Different biological …

The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …

Background Higher-than-normal levels of circulating triglycerides are a risk factor for
ischemic cardiovascular disease. Activation of lipoprotein lipase, an enzyme that is inhibited …

Animal studies indicate that the composition of gut microbiota may be involved in the
progression of insulin resistance to type 2 diabetes. Probiotics and/or prebiotics could be a …

Lipoprotein lipase (LPL) is one of the most important factors in systemic lipid partitioning and
metabolism. It mediates intravascular hydrolysis of triglycerides packed in lipoproteins such …

Recent evidence suggests that probiotics can restore the mucosal barrier integrity,
ameliorate inflammation, and promote homeostasis required for metabolism in obesity by …

The enzyme lipoprotein lipase (LPL), originally identified as the clearing factor lipase,
hydrolyzes triglycerides present in the triglyceride-rich lipoproteins VLDL and chylomicrons …

Colorectal cancer risk is associated with diets high in red meat. Heme, the pigment of red
meat, induces cytotoxicity of colonic contents and elicits epithelial damage and …